Results 281 to 290 of about 4,321,073 (342)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Crystal structure of the sucrose phosphorylase from Alteromonas mediterranea shows a loop transition in the active site. [PDF]

Acta Crystallogr F Struct Biol Commun
Fredslund F, Goux M, Offmann B, Demonceaux M, André-Miral C, Welner D, Teze D.   +6 more
europepmc   +1 more source

Probing the Active Site of Class 3 L-Asparaginase by Mutagenesis: Mutations of the Ser-Lys Tandems of ReAV. [PDF]

Biomolecules
Pokrywka K, Grzechowiak M, Sliwiak J, Worsztynowicz P, Loch JI, Ruszkowski M, Gilski M, Jaskolski M.   +7 more
europepmc   +1 more source

Flexible, nonfused sulfone functionalized polymer with enhanced active site access for photocatalytic sacrificial hydrogen evolution. [PDF]

Sci Adv
Huang TF, Lin KJ, Zhuang YR, Sun YE, Lin WC, Li CH, Lin CC, Chang EC, Chang CL, Liu YC, Hsu LY, Li BH, Chang WL, Pimbaotham P, Bai CY, Huang WH, Hoang DCK, Huynh KDG, Huang YC, Chung CY, Elsenety MM, Chang CA, Huang HN, Jungsuttiwong S, Pao CW, Chen HL, Wu TL, Chang CC, Chen BH, Yang SD, Lin KH, Chou HH.   +31 more
europepmc   +1 more source

Dynamic networks connect the USP14 active site region with the proteasome interaction surface. [PDF]

Protein Sci
Salomonsson J, Sjöstrand L, Eskilson A, Derbyshire D, D'Arcy P, Sunnerhagen M, Ahlner A.   +6 more
europepmc   +1 more source

Htfunclib: Designing Libraries of Active-Site Multipoint Mutants for Protein Optimization

Rosalie Lipsh‐Sokolik, Sarel Jacob Fleishman   +1 more
openalex   +1 more source

Modifications of the Prothrombin Active Site S4 Subpocket Confer Resistance to Dabigatran. [PDF]

Thromb Haemost
Strijbis VJF, Cheung KL, Veizaj D, Rutten T, de Bruin B, Reitsma PH, Verhoef D, Bos MHA.   +7 more
europepmc   +1 more source

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Peroxidase Active Site Activity Assay

2010
Cyclooxygenase enzymes house spatially distinct cyclooxygenase- and peroxidase-active sites. The two-electron reduction of peroxides to their corresponding alcohols by the heme bound in the peroxidase-active site converts the heme to a ferryloxoprotoporyphrin cation radical, with a reductant providing the two electrons necessary to bring the heme back ...
Kelsey C, Duggan, Joel, Musee, Lawrence J, Marnett   +2 more
openaire   +2 more sources