Results 331 to 340 of about 11,841,496 (406)

Final Stages in the Biosynthesis of the [FeFe]-Hydrogenase Active Site. [PDF]

Angew Chem Int Ed Engl
Yu X, Rao G, Britt RD, Rauchfuss TB.
europepmc   +1 more source

Design and validation of a novel dosimetry phantom for motion management audits

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background We present a novel phantom design for conducting end‐to‐end dosimetry audits for respiratory motion management of two anatomical treatment sites. The design enables radiochromic film measurements of the dose administered to the target throughout the respiratory cycle (motion‐included) and the dose delivered to the time‐averaged ...
Alex Burton, Sabeena Beveridge, Nicholas Hardcastle, Silvio Malfitana, Janaka Madamperuma, Rick Franich   +5 more
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya, Calin Reamy, Heng Li, Junghoon Lee, William T. Hrinivich   +4 more
wiley   +1 more source

Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway. [PDF]

Proc Natl Acad Sci U S A
Träger TK, Kyrilis FL, Hamdi F, Tüting C, Alfes M, Hofmann T, Schmidt C, Kastritis PL.   +7 more
europepmc   +1 more source

Risk analysis of the Unity 1.5T MR‐Linac adapt‐to‐shape workflow

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background and Purpose The adapt‐to‐shape (ATS) workflow on the Unity MR‐Linac (Elekta AB, Stockholm, Sweden) allows for full replanning including recontouring and reoptimization5. Additional complexity to this workflow is added when the adaptation involves the use of MIM Maestro (MIM Software, Cleveland, OH) software in conjunction with ...
Jiayi Liang, Eric Aliotta, Neelam Tyagi, Paola Godoy Scripes, Nicolas Côté, Ergys Subashi, Qijie Huang, Lian Sun, Ching‐Yun Chan, Angela Ng, Theresa Wunner, Victoria Brennan, Kaveh Zakeri, James Mechalakos   +13 more
wiley   +1 more source

Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair. [PDF]

Nat Commun
Trasviña-Arenas CH, Dissanayake UC, Tamayo N, Hashemian M, Lin WJ, Demir M, Hoyos-Gonzalez N, Fisher AJ, Cisneros GA, Horvath MP, David SS.   +10 more
europepmc   +1 more source

Enhancing catalytic efficiency of Bacillus subtilis laccase BsCotA through active site pocket design. [PDF]

Appl Microbiol Biotechnol
Hou Y, Zhao L, Yue C, Yang J, Zheng Y, Peng W, Lei L.   +6 more
europepmc   +1 more source

Peri active site catalysis of proline isomerisation is the molecular basis of allomorphy in β-phosphoglucomutase. [PDF]

Commun Biol
Cruz-Navarrete FA, Baxter NJ, Flinders AJ, Buzoianu A, Cliff MJ, Baker PJ, Waltho JP.   +6 more
europepmc   +1 more source

Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors. [PDF]

Nat Commun
Yu H, Kumar S, Frederiksen JW, Kolyadko VN, Pitoc G, Layzer J, Yan A, Rempel R, Francis S, Krishnaswamy S, Sullenger BA.   +10 more
europepmc   +1 more source

Substrate preference, RNA binding and active site versatility of Stenotrophomonas maltophilia nuclease SmNuc1, explained by a structural study. [PDF]

FEBS J
Adámková K, Trundová M, Kovaľ T, Husťáková B, Kolenko P, Dušková J, Skálová T, Dohnálek J.   +7 more
europepmc   +1 more source