Results 71 to 80 of about 4,303,269 (290)

Fenton’s reagent-initiated modification of plantain (Musa paradisiaca) peel biomass – mechanisms of chain propagation and dyes removal from simulated wastewaters [PDF]

Journal of Chemistry Letters
This report describes the mechanisms of Fenton’s reagent-initiated graft-copolymerization of plantain peel biomass (PPB) and that of the polymer-dyes interactions. Methacrylic acid (MAA) was grafted onto the PPB backbone.
Vincent Oninla, Kehinde Awokoya, Loretta Overah, Jonathan Babalola, Ayomide Ademuwagun, Ademola Adetunji, Abosede Ayoola   +6 more
doaj   +1 more source

Copper Active Sites in Biology [PDF]

Chemical Reviews, 2014
Based on its generally accessible I/II redox couple and bioavailability, copper plays a wide variety of roles in nature that mostly involve electron transfer (ET), O2 binding, activation and reduction, NO2− and N2O reduction and substrate activation.
Solomon, Edward I., Heppner, David E., Johnston, Esther M., Ginsbach, Jake W., Cirera, Jordi, Qayyum, Munzarin, Kieber-Emmons, Matthew T., Kjaergaard, Christian H., Hadt, Ryan G., Tian, Li   +9 more
openaire   +3 more sources

An Evolutionary Approach to Drug-Design Using Quantam Binary Particle Swarm Optimization Algorithm

, 2012
The present work provides a new approach to evolve ligand structures which represent possible drug to be docked to the active site of the target protein. The structure is represented as a tree where each non-empty node represents a functional group.
Chowdhury, Arkabandhu, Ghosh, Arnab, Ghosh, Avishek, Hazra, Jubin   +3 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Exploring the inhibitory potential of xanthohumol on MEK1/2: a molecular docking and dynamics simulation investigation

Research in Pharmaceutical Sciences
Background and purpose: Xanthohumol (Xn), a small molecule found in Humulus lupulus, has shown promise as an anti-cancer compound. This in silico study was performed to understand the mechanism of action of Xn as a natural compound on MEK1/2 by ...
Zohreh Gholizadeh Siahmazgi, Shiva Irani, Ali Ghiaseddin, Fereshteh Soutodeh, Zahra Gohari, Jaber Afifeh, Amirreza Pashapouryeganeh, Hilda Samimi, Mahmood Naderi, Parviz Fallah, Vahid Haghpanah   +10 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Rh single atoms on TiO2 dynamically respond to reaction conditions by adapting their site. [PDF]

, 2019
Single-atom catalysts are widely investigated heterogeneous catalysts; however, the identification of the local environment of single atoms under experimental conditions, as well as operando characterization of their structural changes during catalytic ...
Asokan, Chithra, Christopher, Phillip, Graham, George W, Li, Jun, Pan, Xiaoqing, Sautet, Philippe, Tang, Yan, Xu, Mingjie   +7 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Nonuniversal exponents in sandpiles with stochastic particle number transfer

, 2005
We study fixed density sandpiles in which the number of particles transferred to a neighbor on relaxing an active site is determined stochastically by a parameter $p$. Using an argument, the critical density at which an active-absorbing transition occurs
Alava M., Jain K., Jain K., K Jain, Manna S. S., Marro J., Pruessner G., Ruelle P., Schadschneider A.   +8 more
core   +1 more source