Results 1 to 10 of about 3,879,639 (303)
Statement on the active substance acetamiprid [PDF]
EFSA Journal, 2022 Acetamiprid is a pesticide active substance with insecticidal action currently under the third renewal (AIR3) of the Commission implementing regulation (EU) No 844/2012. Following concerns that this substance may pose high risks to humans and the environment, the French authorities asked the Commission to restrict its uses under Article 69 of ...
EFSA Panel on Plant Protection Products and their Residues (PPR) +22 more
openaire +4 more sources
Foods, 2022 In this study, the comparison effects of ultrasound-assisted immersion freezing (UIF) at different ultrasonic power, immersion freezing (IF), and air freezing (AF) on the protein thermal stability, protein structure, and physicochemical properties of ...
Bing Liu +4 more
doaj +1 more source
Discovery of Novel Biphenyl Carboxylic Acid Derivatives as Potent URAT1 Inhibitors
Molecules, 2023 Urate transporter 1 (URAT1) is a clinically validated target for the treatment of hyperuricemia and gout. Due to the absence of protein structures, the molecular design of new URAT1 inhibitors generally resorts to ligand-based approaches.
Xianxin Hou +3 more
doaj +1 more source
Statement on the active substance flupyradifurone [PDF]
EFSA Journal, 2022 Flupyradifurone is a novel butenolide insecticide, first approved as an active substance for use in plant protection products by Commission Implementing Regulation (EU) 2015/2084. Following concerns that this substance may pose high risks to humans and the environment, the French authorities, in November 2020, asked the Commission to restrict its uses ...
EFSA Panel on Plant Protection Products and their Residues (PPR) +22 more
openaire +3 more sources
Three-Step Synthesis of the Antiepileptic Drug Candidate Pynegabine
Molecules, 2023 Pynegabine, an antiepileptic drug candidate in phase I clinical trials, is a structural analog of the marketed drug retigabine with improved chemical stability, strong efficacy, and a better safety margin.
Yi-Jing Sun +4 more
doaj +1 more source
Toxins, 2022 The venom and transcriptome profile of the captive Chinese cobra (Naja atra) is not characterized until now. Here, LC-MS/MS and illumine technology were used to unveil the venom and trascriptome of neonates and adults N. atra specimens.
Xuekui Nie +7 more
doaj +1 more source
Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids
Molecules, 2020 The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring.
Yu-Yan Liang +3 more
doaj +1 more source
Molecules, 2022 C4 variation of 4′-O-demethyl-epipodophyllotoxin (DMEP) is an effective approach to optimize the antitumor spectra of this compound class. Accordingly, two series of novel DMEP derivatives were synthesized, and as expected, the antitumor spectra of these
Wenli Xi +4 more
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Analysis and Evaluation of Nutrient Components in Petals of Different Dahlia Varieties
Shipin gongye ke-ji, 2023 Comparison of differences in the nutritional quality of different dahlia varieties could facilitate the selection of varieties with excellent nutritional quality. This would provide a basis for the resource evaluation and deployment of dahlia.
Zhen LIU +7 more
doaj +1 more source
An efficient and facile access to highly functionalized pyrrole derivatives
Beilstein Journal of Organic Chemistry, 2018 A straightforward and one-pot synthesis of pyrrolo[3,4-c]pyrrole-1,3-diones via Ag(I)-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with N-alkyl maleimide, followed by readily complete oxidation with DDQ, has been successfully developed ...
Meng Gao +5 more
doaj +1 more source