Results 1 to 10 of about 356,045 (168)

Statement on the active substance flupyradifurone [PDF]

EFSA Journal, 2022
Flupyradifurone is a novel butenolide insecticide, first approved as an active substance for use in plant protection products by Commission Implementing Regulation (EU) 2015/2084. Following concerns that this substance may pose high risks to humans and the environment, the French authorities, in November 2020, asked the Commission to restrict its uses ...
EFSA Panel on Plant Protection Products and their Residues (PPR), Antonio Hernandez Jerez, Paulien Adriaanse, Philippe Berny, Tamara Coja, Sabine Duquesne, Andreas Focks, Marina Marinovich, Maurice Millet, Olavi Pelkonen, Silvia Pieper, Aaldrik Tiktak, Christopher Topping, Anneli Widenfalk, Martin Wilks, Gerrit Wolterink, Maj Rundlöf, Alessio Ippolito, Alberto Linguadoca, Laura Martino, Martina Panzarea, Andrea Terron, Annette Aldrich   +22 more
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Statement on the active substance acetamiprid [PDF]

EFSA Journal, 2022
Acetamiprid is a pesticide active substance with insecticidal action currently under the third renewal (AIR3) of the Commission implementing regulation (EU) No 844/2012. Following concerns that this substance may pose high risks to humans and the environment, the French authorities asked the Commission to restrict its uses under Article 69 of ...
EFSA Panel on Plant Protection Products and their Residues (PPR), Antonio Hernandez Jerez, Paulien Adriaanse, Philippe Berny, Tamara Coja, Sabine Duquesne, Andreas Focks, Marina Marinovich, Maurice Millet, Olavi Pelkonen, Silvia Pieper, Aaldrik Tiktak, Christopher Topping, Anneli Widenfalk, Martin Wilks, Gerrit Wolterink, Maj Rundlöf, Alessio Ippolito, Alberto Linguadoca, Laura Martino, Martina Panzarea, Andrea Terron, Annette Aldrich   +22 more
openaire   +4 more sources

Effects of Ultrasound-Assisted Immersion Freezing on the Protein Structure, Physicochemical Properties and Muscle Quality of the Bay Scallop (Argopecten irradians) during Frozen Storage

Foods, 2022
In this study, the comparison effects of ultrasound-assisted immersion freezing (UIF) at different ultrasonic power, immersion freezing (IF), and air freezing (AF) on the protein thermal stability, protein structure, and physicochemical properties of ...
Bing Liu, You-Lin Liao, Liang-Liang Jiang, Miao-Miao Chen, Shan-Bin Yang   +4 more
doaj   +1 more source

Discovery of Novel Biphenyl Carboxylic Acid Derivatives as Potent URAT1 Inhibitors

Molecules, 2023
Urate transporter 1 (URAT1) is a clinically validated target for the treatment of hyperuricemia and gout. Due to the absence of protein structures, the molecular design of new URAT1 inhibitors generally resorts to ligand-based approaches.
Xianxin Hou, Yongcheng Wang, Yajun Yang, Zhiyan Xiao   +3 more
doaj   +1 more source

Three-Step Synthesis of the Antiepileptic Drug Candidate Pynegabine

Molecules, 2023
Pynegabine, an antiepileptic drug candidate in phase I clinical trials, is a structural analog of the marketed drug retigabine with improved chemical stability, strong efficacy, and a better safety margin.
Yi-Jing Sun, Ya-Ling Gong, Shi-Chao Lu, Shi-Peng Zhang, Shu Xu   +4 more
doaj   +1 more source

Venom Variation of Neonate and Adult Chinese Cobras in Captivity Concerning Their Foraging Strategies

Toxins, 2022
The venom and transcriptome profile of the captive Chinese cobra (Naja atra) is not characterized  until now. Here, LC-MS/MS and illumine technology were used to unveil the venom and trascriptome of neonates and adults N. atra specimens.
Xuekui Nie, Qianzi Chen, Chen Wang, Wangxiang Huang, Ren Lai, Qiumin Lu, Qiyi He, Xiaodong Yu   +7 more
doaj   +1 more source

Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids

Molecules, 2020
The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring.
Yu-Yan Liang, Shi-Chao Lu, Ya-Ling Gong, Shu Xu   +3 more
doaj   +1 more source

Antimycobacterial activity of lichen substances

Phytomedicine, 2010
We describe here the extraction and identification of several classes of phenolic compounds from the lichens Parmotrema dilatatum (Vain.) Hale, Parmotrema tinctorum (Nyl.) Hale, Pseudoparmelia sphaerospora (Nyl.) Hale and Usnea subcavata (Motyka) and determined their anti-tubercular activity.
Honda, N. K., Pavan, Fernando Rogério, Coelho, R. G., de Andrade Leite, S. R., Micheletti, A. C., Lopes, T. I. B., Misutsu, M. Y., Beatriz, A., Brum, R. L., Leite, Clarice Queico Fujimura   +9 more
openaire   +3 more sources

Identification of Novel 4′-O-Demethyl-epipodophyllotoxin Derivatives as Antitumor Agents Targeting Topoisomerase II

Molecules, 2022
C4 variation of 4′-O-demethyl-epipodophyllotoxin (DMEP) is an effective approach to optimize the antitumor spectra of this compound class. Accordingly, two series of novel DMEP derivatives were synthesized, and as expected, the antitumor spectra of these
Wenli Xi, Hua Sun, Kenneth F. Bastow, Zhiyan Xiao, Kuo-Hsiung Lee   +4 more
doaj   +1 more source

Hazardous Substances and Activities

, 2021
Abstract This chapter analyses the enormous scope of international instruments addressing hazardous substances and activities by assessing both the regulatory junctures and the specific strategies that governments rely upon to reduce risk.
Wirth, David A., Sachs, Noah M.
openaire   +1 more source