Results 41 to 50 of about 376,531 (312)

Determinants of psychoactive substance use among incarcerated delinquents in Nigeria

, 2013
The objective of the study was to identify the prevalence of psychoactive substance use among incarcerated delinquents in Nigeria and its determinants. The total inmate population of 401 individuals were interviewed over a period of four weeks using an ...
Sheikh, TL, Lasisi, DM, Babalola, OJ, Ike, JO, Agunbiade, S, Ebiti, NW   +5 more
core   +1 more source

Thermal proteome profiling reveals fructose-1,6-bisphosphate as a phosphate donor to activate phosphoglycerate mutase 1

Nature Communications
Deep understanding of sugar metabolite-protein interactions should provide implications on sugar metabolic reprogramming in human physiopathology. Although tremendous efforts have been made for determining individual event, global profiling of such ...
Yanling Zhang, Yafei Cao, Xia Wu, Zhenghui Chen, Bowen Chen, Anhui Wang, Yanshen Guo, Wei Chen, Ruolan Xue, Zihua Liu, Yuanpei Li, Tian Li, Ruiqin Cheng, Ning Zhou, Jing Li, Yuan Liu, Xiaohui Zhao, Huixin Luo, Ming Xu, Houhua Li, Yiqun Geng   +20 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

An Efficient Synthesis of Aryl-Substituted Pyrroles by the Suzuki–Miyaura Coupling Reaction of SEM-Protected Pyrroles

Molecules, 2019
An efficient arylation of SEM-protected pyrroles by the Suzuki–Miyaura coupling reaction has been developed. The reaction can be carried out under mild conditions to provide aryl-substituted pyrroles in moderate to excellent yields.
Keli Cui, Meng Gao, Hongyi Zhao, Dongfeng Zhang, Hong Yan, Haihong Huang   +5 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Trajectories, Transitions and Turning Points: Sports, Substance Misuse and Desistance. [PDF]

, 2012
Despite well-established health benefits of physical exercise (Department of Health 2004; 2010; Pang et al., 2008), sport has played relatively little part in adult alcohol and drug treatment programmes.
Landale, Sarah A, LANDALE, SARAH,A
core  

Changes in Physicochemical Properties and Flavor Characteristics of Rosa roxburghii Tratt. Fruit Vinegar during Fermentation

Shipin gongye ke-ji
This paper investigated the compositional changes of Rosa roxburghii Tratt. fruit vinegar during fermentation. By using Rosa roxburghii Tratt. as raw material and using the whole liquid fermentation technique, fruit vinegar was prepared by fermenting ...
Meiqing MO, Jian ZENG, Jiewen LI, Yuejia WEI, Ziyi JIANG, Aiming BAO, Weijun QIN, Xiangyang GAO   +7 more
doaj   +1 more source

Protective Effect of Bicyclol on Anti-Tuberculosis Drug Induced Liver Injury in Rats

Molecules, 2017
The present study was performed to investigate the effect of bicyclol, a synthetic anti-hepatitis drug with anti-oxidative and anti-inflammatory properties, on anti-tuberculosis (anti-TB) drug-induced liver injury and related mechanisms in rats. Bicyclol
Xin Liu, Manman Zhao, Jiaqi Mi, Hui Chen, Li Sheng, Yan Li   +5 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol

Frontiers in Pharmacology, 2017
10-Chloromethyl-11-demethyl-12-oxo-calanolide (F18), an analog of calanolide A, is a novel potent nonnucleoside reverse transcriptase inhibitor against HIV-1.
Xiangmeng Wu, Qinghao Zhang, Jiamei Guo, Yufei Jia, Ziqian Zhang, Manman Zhao, Yakun Yang, Baolian Wang, Jinping Hu, Li Sheng, Yan Li   +10 more
doaj   +1 more source