Results 91 to 100 of about 3,879,639 (303)
AgriculturePesticide use in agriculture can have negative collateral effects on the environment. In this study, two groups of treatments (G1 and G2) based on active substances (ASs) with different mobility were evaluated in order to determine pesticide residues in ...
M. Dolores Loureiro-Rodríguez +11 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
EFSA Journal, 2017 According to Article 12(1) of Regulation (EC) No 396/2005, EFSA shall provide within 12 months from the date of the inclusion or non‐inclusion of an active substance in Annex I to Directive 91/414/EEC a reasoned opinion on the review of the existing ...
European Food Safety Authority (EFSA)
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Synthesis of 2‑Aryl‑4H‑thiochromen-4-one Derivatives via a Cross-Coupling Reaction
ACS Omega, 2021 Peng Li +3 more
doaj +1 more source
Risk Assessment for Birds and Mammals
EFSA Journal, 2009 The revised Guidance Document on Risk Assessment for Birds and Mammals on the basis of the Scientific Opinion of the PPR Panel on the Science behind the Guidance Document on Risk Assessment for Birds and Mammals (The EFSA Journal (2008) 734: 1–181) and ...
European Food Safety Authority
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Extraction of effective components from
Siliao yanjiu, 2021 Moringa oleifera Lam. is a perennial deciduous tree plant, a traditional Indian herbal medicine. Moringa leaves are rich in nutrients and have antioxidant, anti-inflammatory, antibacterial, and antiviral functions, and moringa leaves are widely used in ...
Wen-wen DONG +4 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Fucoidan reinforce mitophagy in brown adipose tissue thermogenesis to protect against obesity
Carbohydrate Polymer Technologies and ApplicationsBackground: Obesity is a global health issue, characterized by metabolic dysfunction. Brown adipose tissue (BAT) plays a crucial role in energy expenditure and thermogenesis.
Lizhi Peng +7 more
doaj +1 more source