Results 111 to 120 of about 376,531 (312)
Extraction of effective components from
Siliao yanjiu, 2021 Moringa oleifera Lam. is a perennial deciduous tree plant, a traditional Indian herbal medicine. Moringa leaves are rich in nutrients and have antioxidant, anti-inflammatory, antibacterial, and antiviral functions, and moringa leaves are widely used in ...
Wen-wen DONG +4 more
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Kinetics of active substance release from flat biopolymer multilayer films
, 2010 . Polymer films were made of different biodegradable materials. Solid support of model active substance (salicylic acid) was unmodified and modified (crosslinked with glutaraldehyde) chitosan and outside layers were polylactid acid (PLA).
Traczyk, Dariusz +2 more
core
Determination of the exposure surface area per bee for each active substance.
, 2014 S.D.: Standard Deviation (n = 3).g a.s./ha: gram of active substance per hectare.ng a.s./ha: nanogram of active substance per hectare.ng a.s./bee: nanogram of active substance per bee.aThe application rate was corrected with the measured concentration ...
Audrey Buleté (422463) +11 more
core +1 more source
Access New Active Substance and Biosimilar Work Sharing Initiatives
The New Active Substance Work Sharing Initiative has successfully approved several medicines through this international collaboration and continues to foster cooperation and strong relationships between its Access partners.
lsgilbert
core +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Biologically active substance on the basis of beebread
, 2013 The chemical composition of biologically active substance in a beebread is established. The possibility of using drugs on the basis of its therapeutic and preventive agents to compensate lack of biologically active compounds in the human organism, is ...
L T Ahmetova +4 more
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source