Results 61 to 70 of about 4,025,472 (290)

Low Risk Prostate Cancer: Active Treatment or Active Surveillance?

open access: yesActa Clinica Croatica, 2015
The widely used screening for prostate cancer with prostate specific antigen has resulted in identification of potentially lethal prostate cancers at a much more curable stage and has been associated with significant falls in prostate cancer mortality ...
Igor Tomašković
doaj  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

P86 | Active surveillance: what changed?

open access: yesItalian Journal of Medicine
Background: Active surveillance programs aim to prevent the spread of carbapenemase-producing Enterobacterales (CPE). Rectal swab (RS) is used for screening colonized subjects.
doaj   +1 more source

Qualitative insights into how men with low-risk prostate cancer choosing active surveillance negotiate stress and uncertainty

open access: yesBMC Urology, 2017
Background Active surveillance is a management strategy for men diagnosed with early-stage, low-risk prostate cancer in which their cancer is monitored and treatment is delayed.
Emily M. Mader   +11 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Seeing Surveillance: Twenty Years of Surveillance & Society

open access: yes, 2022
This paper reflects on the development of surveillance studies over the twenty years since the first publication of Surveillance & Society. It starts by pointing to key contextual changes that have provided fertile ground for surveillance-focused ...
Fussey, Pete
core   +1 more source

Weekly Influenza Surveillance Report Week 40 2003

open access: yes, 2003
Welcome to the first influenza surveillance report of the 2003/2004-influenza season. This is the fourth year of influenza surveillance using computerised sentinel general practices in Ireland.
National Disease Surveillance Centre (NDSC)   +2 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Prostate cancer “super-active surveillance” era opened by vascular targeted photodynamic therapy

open access: yesResearch and Reports in Urology, 2019
Renato B Corradi,1,2 Thiago C Travassos,1,2 Leonardo O Reis1,21UroScience, Pontifical Catholic University of Campinas, Campinas, SP, Brazil; 2University of Campinas, Campinas, SP, BrazilAbstract: The “super-active surveillance” concept ...
Corradi RB, Travassos TC, Reis LO
doaj  

Twenty Years of Active Bacterial Core Surveillance

open access: yesEmerging Infectious Diseases, 2015
Active Bacterial Core surveillance (ABCs) was established in 1995 as part of the Centers for Disease Control and Prevention Emerging Infections Program (EIP) network to assess the extent of invasive bacterial infections of public health importance.
Gayle Langley   +18 more
doaj   +1 more source

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