Results 81 to 90 of about 610,101 (198)

Actomyosin contractility rotates the cell nucleus [PDF]

, 2013
The nucleus of the eukaryotic cell functions amidst active cytoskeletal filaments, but its response to the stresses carried by these filaments is largely unexplored. We report here the results of studies of the translational and rotational dynamics of the nuclei of single fibroblast cells, with the effects of cell migration suppressed by plating onto ...
arxiv   +1 more source

Functional characterization of nuclear localization and export signals in hepatitis C virus proteins and their role in the membranous web. [PDF]

PLoS ONE, 2014
The hepatitis C virus (HCV) is a positive strand RNA virus of the Flavivirus family that replicates in the cytoplasm of infected hepatocytes. Previously, several nuclear localization signals (NLS) and nuclear export signals (NES) have been identified in ...
Aviad Levin, Christopher J Neufeldt, Daniel Pang, Kristen Wilson, Darci Loewen-Dobler, Michael A Joyce, Richard W Wozniak, D Lorne J Tyrrell   +7 more
doaj   +1 more source

Ascorbate Uptake and Retention by Breast Cancer Cell Lines and the Intracellular Distribution of Sodium-Dependent Vitamin C Transporter 2

Antioxidants, 2023
Ascorbate plays a vital role as a co-factor for a superfamily of enzymes, the 2-oxoglutarate dependent dioxygenases (2-OGDDs), which govern numerous pathways in cancer progression, including the hypoxic response and the epigenetic regulation of gene ...
Citra Praditi, Stephanie M. Bozonet, Gabi U. Dachs, Margreet C. M. Vissers   +3 more
doaj   +1 more source

Multiscale assay of unlabeled neurite dynamics using phase imaging with computational specificity (PICS) [PDF]

arXiv, 2020
Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlying learning and memory. Yet, the unique behavioral properties of neurons make them challenging to study - with phenotypic differences expressed as subtle changes in neuronal ...
arxiv  

Enhanced reaction kinetics in biological cells [PDF]

Nature Physics 4, 134-137 (2008), 2008
The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular medium, as well as on its transport properties : a generic tracer particle freely diffuses as in a standard ...
arxiv   +1 more source

The role of spatial averaging in the precision of gene expression patterns

, 2009
During embryonic development, differentiating cells respond via gene expression to positional cues from morphogen gradients. While gene expression is often highly erratic, embryonic development is precise. We show by theory and simulations that diffusion
Erdmann, Thorsten, Howard, Martin, Wolde, Pieter Rein ten   +2 more
core   +2 more sources

Evolution of the nucleus [PDF]

, 2014
Under a Creative Commons license.The nucleus represents a major evolutionary transition. As a consequence of separating translation from transcription many new functions arose, which likely contributed to the remarkable success of eukaryotic cells.
Adl, Alber, Alberts, Andersen, Basto, Batsios, Bornens, Carvalho-Santos, Carvalho-Santos, Cavalier-Smith, Ciska, Cook, Cronshaw, Dahl, Damien P Devos, Daunderer, De Souza, Debec, Degrasse, Devos, Devos, Ding, Ding, Dittmer, Doucet, DuBois, Embley, Feldherr, Field, Field, Field, Flemming, Friedländer, Gribaldo, Haque, Hartman, Hodges, Hoelz, Hozák, Iwamoto, Kaller, Khodjakov, Khodjakov, King, Koumandou, Krüger, Kuhnert, Lee, Leeson, Li, Lindås, Low, Lu, Makarova, Malone, Mana-Capelli, Mans, Mark C Field, Meier, Neumann, Omer, Pace, Pan, Pearson, Pereira, Pickett-Heaps, Ralph Gräf, Ratcliffe, Rothballer, Rout, Salgado-Garrido, Samson, Sandman, Santarella-Mellwig, Santarella-Mellwig, Schmidt, Schneider, Schulz, Shimi, Starr, Stewart-Hutchinson, Still, Tamura, Tetenbaum-Novatt, Ueda, Wilson, Worman, Xiong, Xu, Zhou   +89 more
core   +3 more sources

REGULATION OF ARABIDOPSIS GDH2 NUCLEAR GENE EXPRESSION DEPENDS ON FUNCTIONAL STATE OF MITOCHONDRIA AND CHLOROPLASTS [PDF]

Journal of Stress Physiology & Biochemistry, 2012
The results of recent studies indicate that expression of some plant nuclear genes depends on functional state of mitochondria and chloroplasts.
Garnik E.Yu., V.I. Tarasenko, V.N. Shmakov, V.I. Bel'kov, Yu.M. Konstantinov   +4 more
doaj  

Robust Segmentation of Cell Nuclei in 3-D Microscopy Images [PDF]

arXiv, 2021
Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability of microscopy images and often over-segment or under-segment the cell nuclei.
arxiv  

The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]

, 2017
One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A., Ali, Nilufar, Amini, Elham, Blumrich, Eva Maria, Datusalia, Ashok K., Fontanet, Paula, García Romero, Ezra Michelet, Ghosh, Shampa, Golpich, Mojtaba, Hegemann, Regina U., Jain, Vishal, Jamwal, Sumit, Joshi, Pooja, Kushwah, Neetu, Lepeta, Katarzyna, Loke, Hannah, Lourenco, Mychael V., Nawrotek, Katarzyna, Paid, Ramesh K., Pastor, Verónica, Piermartiri, Tetsade, Rotermund, Carola, Saini, Vedangana, Salamian, Ahmad, Schaefer, Natascha, Shahidzadeh, Sheila M., Sharma, Mahima, Sharma, Sorabh, Sinha, Jitendra K., Suárez Pozos, Edna, Turner, Anthony J., Vafadari, Benham, Wilson, Yvette   +32 more
core   +2 more sources