Results 111 to 120 of about 4,303,904 (295)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Other title: Kansas Department of Transportation Update

open access: yes, 2007
application/pdf "January 22, 2007." Presentation to the Kansas Legislature, House Transportation and Public Safety Budget Committee, by staff of the Kansas Department of Transportation.Presentation providing a brief overview and update of the overall ...
Kansas. Department of Transportation.
core  

Travel mode choice behavior analysis using multinomial logit models towards creating sustainable college campus: a case study of the University of Toledo, Ohio

open access: yesFrontiers in Future Transportation
By employing descriptive statistics and multinomial logistic regression models, the paper investigates factors that affect the travel mode choice behavior of a college community for both commuting to the campus from their residences and commuting on ...
Taslima Akter, Bhuiyan Monwar Alam
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Incorporating Public Health into Transportation Decision Making [PDF]

open access: yes
ZSB12017-SJAUXInvestments in transportation have the potential to significantly affect public health outcomes. Decisions to build highways, transit, or bikeways, for example, influence how residents and visitors move around a metropolitan area.
San Jose State University. College of Business. Mineta Transportation Institute   +2 more
core   +1 more source

Enhancing shared street accessibility in heritage sites for individuals with visual disabilities: a Canadian perspective

open access: yesFrontiers in Rehabilitation Sciences
IntroductionHeritage sites often pose significant accessibility challenges for individuals with visual disabilities due to their preserved architectural features and strict regulations against modifications.
M. Lakoud   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Investing in transportation to keep Texas economically competitive [PDF]

open access: yes
This current report, It's About Time: Investing in Transportation to Keep TexasEconomically Competitive, updates the February 2009 report by providingan enhanced analysis of the current state of the Texas transportation system,determining the household ...
Texas. Transportation Commission
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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