Results 81 to 90 of about 4,303,904 (295)

“Losing access to outdoor spaces was the biggest challenge for children to be healthy”: pandemic restrictions and community supports for children’s movement in Nova Scotia

Frontiers in Public Health
IntroductionHealth-focused communities can promote physical activity for children by providing them with safe and supportive environments to move.
Maggie Locke, Becky Feicht, Becky Feicht, Michelle R. Stone, Michelle R. Stone, Emily Burke, Emily Burke, Laurene Rehman, Sara F. L. Kirk, Sara F. L. Kirk, Guy Faulkner, Sarah A. Moore, Sarah A. Moore, Sarah A. Moore   +13 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Mobility Infrastructures and Health: Scoping Review of studies in Europe

Public Health Reviews
ObjectivesMovement-friendly environments with infrastructure favouring active mobility are important for promoting physical activity. This scoping literature review aims at identifying the current evidence for links between mobility infrastructures and ...
Sarah Michel, Nicola Banwell, Nicolas Senn   +2 more
doaj   +1 more source

Why don’t they walk or cycle? Reflections on active home–school transportation among Portuguese adolescents: the role of environmental perceptions

Urban, Planning and Transport Research, 2014
The way adolescents travel to school can be an important health promotion strategy. The main objective of this research was to identify the relationships between the Portuguese adolescents’ perception of their neighbourhood and their option for active ...
Nuno Loureiro, Margarida Gaspar de Matos
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

An ecological model of active transportation

, 2018
In this chapter, we introduce the social–ecological approach which posits that human behaviour is influenced by multiple levels of influence. These levels include individual factors (e.g., characteristics of the child such as age, gender and ethnicity ...
Larouche, Richardeditor, Ghekiere, ArianeUGent0001210438728020014649389743968267105E13F81C-927B-11E2-80A9-2F8110BDE39D, Larouche, Guido   +2 more
core  

An investigation into the effect of Coronavirus‐2019 (SARS‐CoV‐2) on active transportation as an opportunity to develop a sustainable tourist destination in the postpandemic era with an emphasis on the local community (Case study: Dorood City, Lorestan Province, Iran)

Юг России: экология, развитие
The aim of this study is structural modeling of the impact of the coronavirus pandemic on active post‐pandemic transport in Dorood City, Iran, emphasising both tourism and development of a long‐term tourist market through the promotion of low‐carbon ...
S. S. Hosseini, Y. Gholami, H. Dolvand, Z. V. Ataev   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Impaired Active Transportation Users [PDF]

74041 15D22-8249Researchers have determined that a significant number of pedestrian and bicycle crashes arise from intoxicated non-motorists (Hutchinson, Kloeden, and Lindsay, 2010).
Singleton, Patrick A., Burbidge, Shaunna K., Avenue Consultants, Inc, Azra, Nuzhat, Subedi, Atul   +4 more
core