Results 91 to 100 of about 27,501 (289)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Virtual Suffering and Awakening of Subjectivity: A Biopolitical Analysis of Black Myth: Wukong

Philosophies
Video games prioritize “fun” and “immersion”, yet suffering can disrupt play. Using phenomenology of emotion, this study examines Black Myth: Wukong as a case where suffering is integral to gameplay and narrative.
Shangyuan Li, Yan Li
doaj   +1 more source

Exergaming as a Strategic Tool in the Fight against Childhood Obesity: A Systematic Review

Journal of Obesity, 2013
Improper use of electronic media is considered a major contributing factor to childhood obesity. However, exergames, a new generation of active games, have made it possible to combine electronic entertainment with physical exercise.
Carminda Maria Goersch Fontenele Lamboglia, Vanina Tereza Barbosa Lopes da Silva, José Eurico de Vasconcelos Filho, Mônica Helena Neves Pereira Pinheiro, Marilene Calderaro da Silva Munguba, Francisco Valmar Isaias Silva Júnior, Fernando Alberto Ramirez de Paula, Carlos Antônio Bruno da Silva   +7 more
doaj   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

Advanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang, Wenfeng Qiu, Weiwen Liang, Xin Zhang, Weijie Liu, Zixin Chen, Yifei Li, Hui Wang, Youchen Tang, Min Li, Rongkang Huang, Zijian Chen, Binghua Ma   +12 more
wiley   +1 more source

Feasibility, design and conduct of a pragmatic randomized controlled trial to reduce overweight and obesity in children: The electronic games to aid motivation to exercise (eGAME) study

BMC Public Health, 2009
Background Childhood obesity has reached epidemic proportions in developed countries. Sedentary screen-based activities such as video gaming are thought to displace active behaviors and are independently associated with obesity. Active video games, where
Rodgers Anthony, Prapavessis Harry, Jiang Yannan, Jull Andrew, Ni Mhurchu Cliona, Foley Louise, Maddison Ralph, Vander Hoorn Stephen, Hohepa Maea, Schaaf David   +9 more
doaj   +1 more source

Stress‐to‐Light Conversion in an Earth‐Abundant Oxide Semiconductor

Advanced Science, EarlyView.
Stress‐to‐light conversion in solids represents a unique photonic functionality, yet it has never been realized in a chemically simple and sustainable material. Here, we show that sustainable semiconductor ZnO exhibits strong near‐infrared (NIR) luminescence under elastic stress when defect‐engineered to stabilize the p‐type state.
Tomoki Uchiyama, Koki Otonari, Reona Omori, Guangfa Yang, Eiji Nishibori, Ying Chen, Xu‐Guang Zheng, Chao‐Nan Xu   +7 more
wiley   +1 more source

Electrohydraulic Folding Ring Actuators for Radially Contracting Applications

Advanced Science, EarlyView.
This work presents an Electrohydraulic Folding Ring Actuator that combines high‐performance electrohydraulic actuation with origami‐inspired folding geometry to achieve constricting radial actuation. This integration yields significant inner lumen constriction, alongside a gripping force capable of holding objects exceeding four times the actuator's ...
Gavril Yong En Tan, Quan Xiong, Jonathan William Ambrose, Zeynep Altundal, Raye Chen‐Hua Yeow   +4 more
wiley   +1 more source

Can active video games make a difference? Differences and similarities between active and passive video gamers regarding motivations, problematic gaming, and mental health among Hungarian secondary school students [PDF]

, 2018
Objective: This study explored the perceptions of video game players on the potential benefits of these games and on the factors associated with these perceptions.
Nyikus, Levente, Smohai, Máté, Hodozsán, Tamás, Puskás, Éva   +3 more
core   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Video Gaming Increases Physical Activity

Journal of Extension, 2010
The 2005 Dietary Guidelines for Americans and Mypramid recommend that children get 60 minutes of moderate level exercise each day. Obesity has become a serious health concern for children and adolescents. Idaho currently has an obesity rate of 10.1% for children ages 10-17.
openaire   +2 more sources