Results 121 to 130 of about 32,159 (165)
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Activins and activin antagonists in the human ovary and ovarian cancer
Molecular and Cellular Endocrinology, 2015Activins are members of the transforming growth factor β superfamily that play an important role in controlling cell proliferation and differentiation in many organs including the ovary. It is essential that activin signalling be tightly regulated as imbalances can lead to uncontrolled cell proliferation and cancer. This review describes the expression
Karen L, Reader, Elspeth, Gold
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Localization of an activin/activin receptor system in the porcine ovary
Molecular Reproduction and Development, 2001AbstractThe aim of this study was to locate a possible activin/activin receptor system within porcine ovaries containing functional corpora lutea. In situ hybridization was used to assess the gene expression of βA‐ and βB‐activin subunits, and immunohistochemical studies were done to detect activin‐A protein and activin receptor type II.
van den Hurk, R., van der Pavert, S.A.
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Inhibins and activins in pregnancy
Molecular and Cellular Endocrinology, 2004Human placenta, decidua, and fetal membranes are the major sites of production and secretion of inhibin A and activin A in maternal serum, amniotic fluid, and umbilical cord blood. These tissues also express follistatin-related gene and betaglycan, the binding proteins of activin A and inhibin A, respectively, recently identified. They show a different
FLORIO, P. +5 more
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Biochemical and Biophysical Research Communications, 1994
Activin A-, AB- and B-responding cells were characterized by their responsiveness in cytosolic free calcium ([Ca2+])i) to four hypothalamic releasing hormones, CRH, GHRH, TRH and GnRH. First, rat pituitary cells responding to activin A, AB and B in [Ca2+]i were determined in a mixed population of pituitary cells. The populations of the activin A-, AB-,
K, Tasaka +7 more
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Activin A-, AB- and B-responding cells were characterized by their responsiveness in cytosolic free calcium ([Ca2+])i) to four hypothalamic releasing hormones, CRH, GHRH, TRH and GnRH. First, rat pituitary cells responding to activin A, AB and B in [Ca2+]i were determined in a mixed population of pituitary cells. The populations of the activin A-, AB-,
K, Tasaka +7 more
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Activins and Inhibins and Their Signaling
Annals of the New York Academy of Sciences, 2004Abstract: Activins and inhibins, which were discovered by virtue of their abilities to stimulate or inhibit, respectively, the secretion of FSH, are members of the transforming growth factor‐β (TGFβ) superfamily and exert a broad range of effects on the diffentiation, proliferation and functions of numerous cell types.
Wylie, Vale +5 more
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Blood, 2011
In this issue of Blood , Sierra-Filardi and colleagues shed new light on the still poorly understood proinflammatory role of Activin A in macrophage polarization ...
SOZZANI, Silvano, T. Musso
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In this issue of Blood , Sierra-Filardi and colleagues shed new light on the still poorly understood proinflammatory role of Activin A in macrophage polarization ...
SOZZANI, Silvano, T. Musso
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2011
Activins, members of the TGF-β family, are multifunctional growth and differentiation factors. Activins regulate glucose/energy metabolism by promoting the differentiation of insulin-producing and -responsive cells, and regulating function of the differentiated cells.
Osamu, Hashimoto, Masayuki, Funaba
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Activins, members of the TGF-β family, are multifunctional growth and differentiation factors. Activins regulate glucose/energy metabolism by promoting the differentiation of insulin-producing and -responsive cells, and regulating function of the differentiated cells.
Osamu, Hashimoto, Masayuki, Funaba
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2011
Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo, Kang, Chih-Rong, Shyr
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Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo, Kang, Chih-Rong, Shyr
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Journal of Cellular Physiology, 2010
AbstractActivin A, is a multifunctional cytokine of the transforming growth factor‐β superfamily of growth factors. This molecule has been shown to be implicated in the regulation of a broad range of important biological functions including bone remodelling.
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AbstractActivin A, is a multifunctional cytokine of the transforming growth factor‐β superfamily of growth factors. This molecule has been shown to be implicated in the regulation of a broad range of important biological functions including bone remodelling.
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Inhibins, activins and follistatins
Journal of Steroid Biochemistry, 1989Inhibins are proteins consisting of two subunits, 18 K alpha- and 14 K beta-subunits, linked by disulfide bonds. Two forms of inhibins A and B consisting of a common alpha-subunit and a similar but distinguishable beta-subunit specifically suppress the secretion and cell content of FSH in a delayed action.
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