Results 251 to 260 of about 21,210,719 (287)

Anti-activin treatment increases T cell infiltration in breast and pancreatic tumours and promotes survival in a SMAD4-null mouse pancreatic cancer model

McCluney S, Park D, Miller DS, Mehić M, Bloxham RD, De Vries E, Wang X, Boeing S, D’Antonio L, Wieteska Ł, Pyeatt G, Strohbuecker S, Chakravarty P, Maia De Oliveira T, Wilkinson RW, Hyvönen M, Hunt J, Hill CS.   +17 more
europepmc   +1 more source

Activin Actions in Adipocytes.

J Clin Endocrinol Metab
Ongaro L, Bernard DJ.
europepmc   +1 more source

Simplified In Vitro Generation of Human Gastruloids for Modelling Early Development

Azami T, Patton EE, Nichols J.
europepmc   +1 more source

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Activin A and Activin Receptors in Thyroid Cancer

Thyroid, 2001
Proliferation is controlled by a network of mitogenic and growth inhibitory factors. Transforming growth factor-beta1 (TGF-beta1) and activin A are the most important growth inhibitors of benign follicular epithelial cells of the human thyroid. The effects of these substances on malignant primary thyrocytes are not known.
K M, Schulte, C, Jonas, R, Krebs, H D, Röher   +3 more
openaire   +2 more sources

Bovine preantral follicles and activin: Immunohistochemistry for activin and activin receptor and the effect of bovine activin a in vitro

Theriogenology, 1997
Activin was originally isolated from follicular fluid as a factor stimulating FSH from the pituitary. Recent studies also suggest a local role for activin in the development of preantral and early antral follicles. In the present study, activin and activin receptor immunoreactivity are shown in oocyte and granulosa cells of bovine preantral follicles ...
S C, Hulshof, J R, Figueiredo, J F, Beckers, M M, Bevers, H, Vanderstichele, R, van den Hurk   +5 more
openaire   +2 more sources

Activin A In Brain Injury

2007
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale, Gazzolo, Diego, Luisi, Stefano, Petraglia, Felice   +3 more
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Activin A in Perinatal Brain Injury

Neuropediatrics, 2015
Activin A is a multifunctional growth and differentiation factor belonging to the transforming growth factor β (TGF-β) family. Growing evidence indicates its role as a neurotrophic factor and regulator of synaptic transmission as well as its functional importance in several types of cerebral injury.
Florian A, Brackmann, Christian, Alzheimer, Regina, Trollmann   +2 more
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Activin A Induces Apoptotic Cell Death

Biochemical and Biophysical Research Communications, 1993
Activins, members of a family of the transforming growth factor beta (TGF beta), are involved in the regulation of multiple biological events. We found a novel effect of activin A on hybridoma and myeloma cell lines. Activin A exhibited a cytotoxic effect on interleukin-6 (IL-6)-dependent B9 cells and induced a significant increase in the proportion of
T, Nishihara, N, Okahashi, N, Ueda
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Activin A and bone metastasis

Journal of Cellular Physiology, 2010
AbstractActivin A, is a multifunctional cytokine of the transforming growth factor‐β superfamily of growth factors. This molecule has been shown to be implicated in the regulation of a broad range of important biological functions including bone remodelling.
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Activin as a cell differentiation factor

Progress in Growth Factor Research, 1990
Activin, originally discovered as a polypeptide hormone that is capable of stimulating follicle-stimulating hormone secretion from pituitary cells in vitro, has recently been found to have a much wider range of biological activities. There are a number of reports of activin action as a cell differentiation factor on various types of cells rather than ...
N, Ueno, S, Nishimatsu, K, Murakami
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