Results 201 to 210 of about 5,391 (252)
Activins and Their Receptors in Female Reproduction
Biochemistry and Cell Biology, 2000 Activins are growth and differentiation factors belonging to the transforming growth factor-β superfamily. They are dimeric proteins consisting of two inhibin β subunits. The structure of activins is highly conserved during vertebrate evolution. Activins
Chun Peng
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Theriogenology, 1997
Activin was originally isolated from follicular fluid as a factor stimulating FSH from the pituitary. Recent studies also suggest a local role for activin in the development of preantral and early antral follicles. In the present study, activin and activin receptor immunoreactivity are shown in oocyte and granulosa cells of bovine preantral follicles ...
S C, Hulshof +5 more
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Activin was originally isolated from follicular fluid as a factor stimulating FSH from the pituitary. Recent studies also suggest a local role for activin in the development of preantral and early antral follicles. In the present study, activin and activin receptor immunoreactivity are shown in oocyte and granulosa cells of bovine preantral follicles ...
S C, Hulshof +5 more
openaire +2 more sources
Activin A and Activin Receptors in Thyroid Cancer
Thyroid, 2001Proliferation is controlled by a network of mitogenic and growth inhibitory factors. Transforming growth factor-beta1 (TGF-beta1) and activin A are the most important growth inhibitors of benign follicular epithelial cells of the human thyroid. The effects of these substances on malignant primary thyrocytes are not known.
K M, Schulte +3 more
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Activins and activin antagonists in the prostate and prostate cancer
Molecular and Cellular Endocrinology, 2012Activins are members of the TGF-β super-family. There are 4 mammalian activin subunits (β(A), β(B), β(C) and β(E)) that combine to form functional proteins. The role of activin A (β(A)β(A)) is well characterized and known to be a potent growth and differentiation factor.
Elspeth, Gold, Gail, Risbridger
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1988
Publisher Summary This chapter discusses the isolation, structure, characterization, and biosynthesis of inhibins and activins. The two pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) which regulate the development and maturation of the gonad, are identified.
N, Ling +7 more
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Publisher Summary This chapter discusses the isolation, structure, characterization, and biosynthesis of inhibins and activins. The two pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) which regulate the development and maturation of the gonad, are identified.
N, Ling +7 more
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Activin, Activin-Binding Protein (Follistatin) and Activin Receptor
1993The principal regulators of the pituitary gonadotropins LH and FSH in mammals are the gonadotropin-releasing hormone (GnRH) from the hypothalamus and the gonadal steroids.
Hiromu Sugino +3 more
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Vitamins and Hormones, 2011
Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo Kang, Chih-Rong Shyr
exaly +3 more sources
Activins are the members of transforming growth factor β superfamily and act as secreted proteins; they were originally identified with a reproductive function, acting as endocrine-derived regulators of pituitary follicular stimulating hormone. In recent years, additional functions of activins have been discovered, including a regulatory role during ...
Hong-Yo Kang, Chih-Rong Shyr
exaly +3 more sources
2007
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale +3 more
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Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale +3 more
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Activins and activin antagonists in the human ovary and ovarian cancer
Molecular and Cellular Endocrinology, 2015Activins are members of the transforming growth factor β superfamily that play an important role in controlling cell proliferation and differentiation in many organs including the ovary. It is essential that activin signalling be tightly regulated as imbalances can lead to uncontrolled cell proliferation and cancer. This review describes the expression
Karen L, Reader, Elspeth, Gold
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Localization of an activin/activin receptor system in the porcine ovary
Molecular Reproduction and Development, 2001AbstractThe aim of this study was to locate a possible activin/activin receptor system within porcine ovaries containing functional corpora lutea. In situ hybridization was used to assess the gene expression of βA‐ and βB‐activin subunits, and immunohistochemical studies were done to detect activin‐A protein and activin receptor type II.
van den Hurk, R., van der Pavert, S.A.
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