Results 151 to 160 of about 14,136,893 (299)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Statistics and Graphing [PDF]

open access: yes
Statistics play a vital role in the scientific enterprise. This activity provides background information and tutorials on basic statistics (mean, median, standard deviation, etc.) used in science.
Matt Laposata
core  

The Internet Activities of FiBL [PDF]

open access: yes, 2002
The poster presents the main internet sites maintained by FIBL in 2002: www.fibl.org www.oekolandbau.de http://www.organicxseeds ...
Alföldi, Thomas   +5 more
core  

Enzymatic Activity in the M Band [PDF]

open access: bronze, 1959
Russell J. Barrnett, George E. Palade
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Nuclear Power Plant [PDF]

open access: yes
This lesson introduces students to the basics of nuclear energy production. Topics include radioisotope thermoelectric generators, natural decay of radioactive isotopes, and chain reactions.
John Pratte
core  

Hospitaller activities in medieval Malta [PDF]

open access: yes, 2007
The Medieval Period in the Mediterranean World is generaly considered to cover a period of about a thousand years, and is considered to initiate with the end of the Roman era heralded by the division of the Roman Empure into two parts between the sons of
Savona-Ventura, Charles
core  

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