Results 161 to 170 of about 23,920,837 (347)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Human Propulsion [PDF]

open access: yes
This lesson points out that the motion of objects (velocity or acceleration) is almost never constant, and applies this idea to the motion of a person walking.
John Pratte
core  

UA12/2/34 Student Handbook [PDF]

open access: yes, 1963
1963-64 student handbook created for WKU students which gives a history of WKU, academic information regarding enrollment, services and facilities available to students, campus map and ...
WKU Student Activities, Organizations & Leadership
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Statistics and Graphing [PDF]

open access: yes
Statistics play a vital role in the scientific enterprise. This activity provides background information and tutorials on basic statistics (mean, median, standard deviation, etc.) used in science.
Matt Laposata
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Nuclear Power Plant [PDF]

open access: yes
This lesson introduces students to the basics of nuclear energy production. Topics include radioisotope thermoelectric generators, natural decay of radioactive isotopes, and chain reactions.
John Pratte
core  

CBERN - The First Six Years: Challenges and Achievements [PDF]

open access: yes, 2012
CBERN was created in 2006. Its mandate was to create a network able to address critically, persuasively and visibly the foundational role of ethics in business and economic development. The task facing the network was significant. The field was fractured
Canadian Business Ethics Research Network (CBERN)
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Atmosphere [PDF]

open access: yes
This exercise is intended to reinforce the importance of Earth's atmosphere to living organisms. Topics include our bodies' interactions with the atmosphere; its composition and structure; and natural changes in the atmosphere (weather).
Chris Fox
core  

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