Results 91 to 100 of about 4,486,733 (367)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Improving the Delivery of Function-Directed Care During Acute Hospitalizations: Methods to Develop and Validate the Functional Assessment in Acute Care Multidimensional Computerized Adaptive Test (FAMCAT)

Archives of Rehabilitation Research and Clinical Translation, 2021
Objective:: To (1) develop a patient-reported, multidomain functional assessment tool focused on medically ill patients in acute care settings; (2) characterize the measure's psychometric performance; and (3) establish clinically actionable score strata ...
Andrea L. Cheville, MD, MSCE, Chun Wang, PhD, Kathleen J. Yost, PhD, Jeanne A. Teresi, EdD, PhD, Mildred Ramirez, PhD, Katja Ocepek-Welikson, M Phil, Pengsheng Ni, MD, MPH, Elizabeth Marfeo, PhD, MPH, OTR/L, Tamra Keeney, DPT, PhD, Jeffrey R. Basford, MD, PhD, David J. Weiss, PhD   +10 more
doaj  

Cardio-metabolic and socio-demographic risk factors associated with dependency in basic and instrumental activities of daily living among older Iranian adults: Bushehr elderly health program

BMC Geriatrics, 2021
Background Iran’s population is aging. Disability is a major public health problem for older adults, not only in Iran but all over the world. The purpose of this study was to investigate the relationship between cardio-metabolic and socio-demographic ...
Kazem Khalagi, Akram Ansarifar, Noushin Fahimfar, Mahnaz Sanjari, Safoora Gharibzdeh, Farshad Sharifi, Gita Shafiee, Ramin Heshmat, Iraj Nabipour, Bagher Larijani, Afshin Ostovar   +10 more
doaj   +1 more source

Sensor Fusion for Recognition of Activities of Daily Living [PDF]

Sensors, 2018
Activity of daily living (ADL) is a significant predictor of the independence and functional capabilities of an individual. Measurements of ADLs help to indicate one’s health status and capabilities of quality living. Recently, the most common ways to capture ADL data are far from automation, including a costly 24/7 observation by a designated ...
Jiaxuan Wu, Yunfei Feng, Peng Sun
openaire   +4 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

All Limbs Lead to the Trunk [PDF]

, 2017
This poster describes the development of and the psychometric properties of the trunk scale that measures the voluntary motor ability in the thoracic and upper lumbar regions.
Atkinson, PhD, PT, Darryn, Graves, PhD, Daniel E.   +1 more
core   +1 more source

A randomized trial of a multicomponent home intervention to reduce functional difficulties in older adults [PDF]

, 2006
OBJECTIVES: To test the efficacy of a multicomponent intervention to reduce functional difficulties, fear of falling, and home hazards and enhance self-efficacy and adaptive coping in older adults with chronic conditions. DESIGN: A prospective, two-group,
Arfken, Bandura, Bradley, Bruce, Cohen, Corcoran, Cumming, Elkan, Ettinger, Ferrucci, Folstein, Fried, Gill, Gill, Gill, Gitlin, Gitlin, Gitlin, Greiner, Hinojosa, Hortobagyi, Kravitz, Kressig, Lawton, Lorig, Mann, Manton, Marshall, Morris, Naik, Powell, Radloff, Rich, Schulz, Shumway-Cook, Spillman, Stuck, Tennstedt, Tinetti, Tinetti, Tinetti, Van Haastregt, Verbrugge, Vladeck, Wrosch   +44 more
core   +2 more sources

Activities of Daily Living

, 2016
Measurement of ability or inability to perform activities of daily living (ADLs) is important to in describing the functional status of a person and then implementing an intervention. Evaluations of ADLs are mainly used in nursing and in rehabilitation of people with disabilities and the elderly.
openaire   +5 more sources

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Older adults, falls and technologies for independent living: a life space approach [PDF]

, 2011
This paper draws attention to the need for further understanding of the fine details of routine and taken-for-granted daily activities and mobility. It argues that such understanding is critical if technologies designed to mitigate the negative impacts ...
BEN DROMEY, Camarinha-Matos, CATHY BAILEY, CLIODHNA NI SCANAILL, Cumming, Gannon, Heywood, Lebbon, Lewin, McKee, Milligan, Morse, Peace, Peel, Rowles, TIMOTHY G. FORAN, Tinker   +16 more
core   +1 more source