Results 81 to 90 of about 1,947,838 (286)

Hip fracture. Preliminary results supporting significative correlations between the psychological wellbeing of patients and their relative caregivers [PDF]

, 2016
Background and aim. Hip fracture is one of the major causes of loss of self-sufficiency in older patients. The associated caregiving rehabilitation task often falls to the lot of a member of the patient’s family.
Bellanti, G ., Eleuteri, S., Falaschi, P.   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Family Dynamics and Auditory Verbal Therapy [PDF]

, 2018
Auditory Verbal Therapy (AVT) is an intervention approach that is structured around caregiver involvement. While this model emphasizes the need for interventions to occur throughout the week within activities of daily living, many families have different
Baldwin, Casey
core   +2 more sources

Rasch analysis of the Nottingham Extended Activities of Daily Living Scale [PDF]

, 2011
Background and purpose: The Nottingham Extended Activities of Daily Living (EADL) Scale is frequently used in clinical practice and research in rehabilitation to assess patients’ independence in activities of daily living.
das Nair, Roshan, Lincoln, Nadina, Moreton, Bryan   +2 more
core   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Measuring unmet need for social care among older people

, 2011
Recent spending cuts in the area of adult social care raise policy concerns about the proportion of older people whose need for social care is not met. Such concerns are emphasised in the context of population ageing and other demographic changes.
Evandrou, Maria, Falkingham, Jane, Luff, Rebekah, Shaw, Richard, Vlachantoni, Athina, Willis, Rosalind   +5 more
core  

The Use of Quiet Books with People with Late Stage Dementia: A Case Study [PDF]

, 2017
Discussion of the use of Quiet Books as a method to provide sensory stimulation to people with late stage dementia to reduce agitation and combativeness with activities of daily living. Supporting literature for the use of sensory stimulation with people
Chabot, OTD, OTR/L, CLIPP, CAPS, CLA, Monique, Galaton, MOT, OTR/L, Jaime   +1 more
core   +1 more source

Determinants of Activity Levels in African Americans With Mild Cognitive Impairment. [PDF]

, 2016
Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and ...
Casten, PhD, Robin J., Leiby, PhD, Benjamin E., Rovner, MD, Barry W.   +2 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source