Results 61 to 70 of about 167,138,734 (281)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Impact of spinal pain on daily living activities in postmenopausal women working in agriculture [PDF]

, 2017
Introduction and objective Postmenopausal women working in agriculture suffer from spinal pain for two overlapping reasons, the first is related to the menopause and the second to the specificity of rural work, which includes lifting heavy objects and ...
Sarecka-Hujar, Beata, Saran, Tomasz, Beata Sarecka-Hujar, Tomasz Saran, Iwona Bojar, Raczkiewicz, Dorota, Dorota Raczkiewicz, Owoc, Alfred, Bojar, Iwona, Alfred Owoc   +9 more
core   +2 more sources

Prevalence of Neck Pain and its effects on Activities of Daily Living among dentists working in Faisalabad

Rehman Journal of Health Sciences, 2020
Introduction: Chronic Neck Pain has become a severe health and socioeconomic problem in modern era. It is a leading cause of physical disability and about 70% of population experience neck pain in their lives.
Fatima Tariq, Muhammad Kashif, Aiman Mehmood, Amna Quraishi   +3 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A compilation of energy costs of physical activities. [PDF]

, 2005
OBJECTIVES: There were two objectives: first, to review the existing data on energy costs of specified activities in the light of the recommendations made by the Joint Food and Agriculture Organization/World Health Organization/United Nations University (
Vaz, Mario, Draper, A., Draper, Alizon, Karaolis, Nadine, Vaz, M., Shetty, P., Karaolis, N., Shetty, Prakash   +7 more
core   +1 more source

The association of post-stroke changes in body mass index with activity of daily living and instrumental activity of daily living trajectories: A multi-cohort analysis

The Journal of Nutrition, Health and Aging
Objectives: The determinants of functional limitation trajectories after stroke remain scarce. This study aimed to investigate the association of early body mass index (BMI) changes with trajectories of activities of daily living (ADLs) and instrumental ...
Guillaume Chambinaud, Aurore Fayosse, Aline Dugravot, Benjamin Landré, Alexis Schnitzler, Archana Singh-Manoux, Séverine Sabia, Louis Jacob   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship Between Depression and Daily Activities Among Older Adults in Zahedan, Iran, 2024 [PDF]

علوم بهداشتی ایران
Background and Purpose: The inability to perform daily activities can have detrimental effects, such as reduced quality of life and social participation, and is a risk factor for anxiety and depression.
Shima Khosravi, Mohammad Ali Yadegary, Ali Aliabadi, Azizollah Arbabisarjou, Hossein Ansari   +4 more
doaj