Results 51 to 60 of about 425,946 (294)
Rehman Journal of Health Sciences, 2020 Introduction: Chronic Neck Pain has become a severe health and socioeconomic problem in modern era. It is a leading cause of physical disability and about 70% of population experience neck pain in their lives.
Fatima Tariq +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Journal of Nutrition, Health and AgingObjectives: The determinants of functional limitation trajectories after stroke remain scarce. This study aimed to investigate the association of early body mass index (BMI) changes with trajectories of activities of daily living (ADLs) and instrumental ...
Guillaume Chambinaud +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Relationship Between Depression and Daily Activities Among Older Adults in Zahedan, Iran, 2024 [PDF]
علوم بهداشتی ایرانBackground and Purpose: The inability to perform daily activities can have detrimental effects, such as reduced quality of life and social participation, and is a risk factor for anxiety and depression.
Shima Khosravi +4 more
doaj
Performance of healthy adult subjects in Glittre ADL-test
Fisioterapia e Pesquisa, 2015 The Glittre ADL-test (TGlittre), validated to assess the functional capacity of patients with chronic obstructive pulmonary disease, has as outcome the shortest total time required to complete it.
Cardine Martins dos Reis +5 more
doaj +1 more source
Critical review of the justification of limitations in physical therapy and activities of daily living in cardiac surgery patients [PDF]
, 2022 V. V. Vitomskyi
openalex +1 more source