Results 91 to 100 of about 10,307,474 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Let’s get physical : exploring the perceptions of physical activity participation and counselling among Australian medical students

, 2017
Physicians have been identified as important promoters of physical activity (PA) – a modifiable risk factor for a range of chronic diseases. Evidence suggests, however, that physicians may not always be equipped to provide PA counselling due to a lack of
George, Emma S. (R17418), Townsend, Kathryn E. (R18646), MacMillan, Freya (R17633)   +2 more
core  

Effectiveness of Intervention Strategies to Increase Adolescents’ Physical Activity and Reduce Sedentary Time in Secondary School Settings, Including Factors Related to Implementation: A Systematic Review and Meta-Analysis

Sports Medicine - Open
Background Globally, just one in five adolescents meet physical activity guidelines and three-quarters of the school day is spent sitting. It is unclear which types of school-based interventions strategies increase physical activity and reduce sedentary ...
Ana María Contardo Ayala, Kate Parker, Emiliano Mazzoli, Natalie Lander, Nicola D. Ridgers, Anna Timperio, David R. Lubans, Gavin Abbott, Harriet Koorts, Jo Salmon   +9 more
doaj   +1 more source

QUALITY OF LIFE, PERCEIVED STIGMA, ACTIVITY AND PARTICIPATION OF PEOPLE WITH LEPROSY-RELATED DISABILITIES IN SOUTH-EAST NEPAL

Disability, CBR and Inclusive Development, 2011
In Nepal, many people live with leprosy-related disabilities. The objective of this study was to evaluate differences in socio-economic characteristics, quality of life (QOL), perceived stigma, activity and participation among people affected by leprosy ...
Huib Cornielje, Wim van Brakel, Corline Brouwers   +2 more
doaj   +1 more source

Identifying Activity

SIAM Journal on Optimization, 2011
Identification of active constraints in constrained optimization is of interest from both practical and theoretical viewpoints, as it holds the promise of reducing an inequality-constrained problem to an equality-constrained problem, in a neighborhood of a solution. We study this issue in the more general setting of composite nonsmooth minimization, in
Adrian S. Lewis, Stephen J. Wright 0001
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Hierarchical System of Strategies for Innovative Management of the Development of Hotels and Catering Enterprises on an Active Adaptive Basis [PDF]

Problemi Ekonomiki, 2018
The aim of the article is forming a hierarchical system of strategies for innovative management of the development of hotels and restaurant enterprises on an active adaptive basis under modern market conditions.
Prokhorova Viktoriia V. , Davydova Oksana Yu.   +1 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Community-based enhanced adherence counseling among people living with HIV in Ethiopia: outcomes and key predictors of viral suppression

AIDS Research and Therapy
Background Community-based enhanced adherence counseling (CEAC) is person-centered intervention provided to PLHIV on ART and with unsuppressed viral load (VL) in community settings.
Endris Seid Ebrahim, Dawit A. Tsegaye, Gashaw A. Biks, Fisseha Shiferie, Liyu Wegayehu, Asayehegn Tekeste, Gobena Seboka, Ambachew Tefera, Legese A. Mekuria, Adrienne Hayes, Wondwossen A. Alemayehu, Endalkachew Melese, Joseph Odu, Sangeeta Mookherji, Emily Liddell, Afework Negash   +15 more
doaj   +1 more source