EFFECTS OF SODIUM AND POTASSIUM IONS ON THE ATPASE ACTIVITY OF RAT KIDNEY MITOCHONDRIA
Munekazu Gemba, Juro Ueda
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Reliability and validity of the Sinhala version of the physical activity questionnaire for older children (PAQ-C). [PDF]
Liyanage E, Jayasinghe C, Liyanage I.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Persistent entropy links irregularities in daily and weekly rest and activity cycles during gestation week 22 and 32 to maternal and neonate health outcomes: A prospective cohort study. [PDF]
Vagus S, Casey TM, George UZ.
europepmc +1 more source
Effect of exercise on labeled blood pool activity. [PDF]
Richard J. Burns
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Maternal physical activity during pregnancy is associated with changes of brain cortical development and executive function in 8-year-old children. [PDF]
Na X +6 more
europepmc +1 more source

