Results 231 to 240 of about 20,351,713 (358)
Relationships between arm and leg real-life activity and clinical assessments in individuals with disabling spasticity after stroke. [PDF]
Andersson S +3 more
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Non-physiological potassium concentrations in commercial culture media trigger acute seizure-like activity in human iPSC-derived neurons. [PDF]
Lyckenvik T +10 more
europepmc +1 more source
Computational Mutagenesis Models for Protein Activity and Stability Analysis
Bill Zhan
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Accelerometer-measured physical activity: comparing young adult football players and non-athletic peers. [PDF]
Jovanovic S +4 more
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
ApoJ regulates endothelial lipase activity and stability. [PDF]
Jean-Baptiste UL +5 more
europepmc +1 more source

