Results 61 to 70 of about 828,088 (215)
Radon control in buildings is being performed for decades in different countries of the world, including Russia. However, there is a lack of unified standard for the assessment of the uncertainty of the results of the control, considering the protocol ...
A. A. Tsapalov +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A systematic investigation of the electrochemically generated superoxide radical (O2●-) has been conducted in the presence of some flavonoids. Cyclic voltammetry was used to generate O2●- by reducing the molecular oxygen in DMSO at room temperature.
Safeer AHMED, Faria SHAKEEL
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Application of several activity coefficient models to water-organic-electrolyte aerosols of atmospheric interest [PDF]
In this work, existing and modified activity coefficient models are examined in order to assess their capabilities to describe the properties of aqueous solution droplets relevant in the atmosphere.
T. Raatikainen, A. Laaksonen
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Characterization of Acoustic Emissions from Concrete Based on Energy Activity Coefficient
Single-stage compression loading experiments were carried out on concrete specimens of various strengths to explore the characteristic parameters of the acoustic emission signal and its damage evolution law in the concrete damage process. These specimens
Lei Liu +5 more
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Protocol for measuring erythrocyte glutathione reductase activity coefficient to assess riboflavin status. [PDF]
Parkington DA, Koulman A, Jones KS.
europepmc +1 more source

