Results 101 to 110 of about 16,937,312 (352)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Martian Ionospheric Cold Hydrogen Ion Escape at Solar Maximum: First Observations

open access: yesThe Astrophysical Journal
The water escape from Mars to space could be in the form of hydrogen and oxygen ions as driven by solar wind–Mars interactions. Although oxygen ion escape has been extensively investigated, the H ^+ escape rate was measured only at solar minimum.
Qi Xu   +10 more
doaj   +1 more source

Spatial Characteristics and Activity Space Pattern Analysis of Dhaka City, Bangladesh

open access: yesUrban Science, 2019
Although a handful of studies have begun to integrate activity space within travel behavior analysis in the European and United States (U.S.) contexts, few studies have measured the size, structure, and implications of human activity spaces in the ...
Naila Sharmeen, Douglas Houston
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A Physics-informed Deep Learning Model for the Magnetic Classification of Solar Active Regions

open access: yesThe Astrophysical Journal Supplement Series
Solar active regions (ARs) are the source of solar eruptive events such as flares. The morphology of sunspots within ARs is closely related to solar eruptive activity.
Ming Li   +5 more
doaj   +1 more source

Continuous space representations of human activity spaces

open access: yes, 2005
Arbeitsberichte Verkehrs- und Raumplanung ...
Vaze, Vikrant S.   +2 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Operational Solar Flare Ensemble Forecasting Model for Full-disk Active Regions

open access: yesThe Astrophysical Journal Supplement Series
Solar flares are explosive releases of magnetic energy in localized regions of the solar atmosphere that threaten the safety of solar–terrestrial technological systems, making their forecasting critical for space-weather-forecasting support services ...
Ming Li   +5 more
doaj   +1 more source

Spaces seeking activities - activities seeking spaces: Evaluation and policy design of neighbourhood-wide urban community spaces

open access: yesCity, Culture and Society
Cities thrive on the vibrant interplay of community-driven initiatives and the adaptive reuse of public spaces that foster socio-cultural activities, enriching civic life. However, these grassroots efforts often confront challenges such as spatial inadequacies caused by bureaucratic zoning policies and the scarcity of affordable real estate.
Blečić, Ivan   +3 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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