Results 121 to 130 of about 4,049,670 (304)

Amazing Space: The Helix Nebula - NGC 7293 Lithograph [PDF]

open access: yes, 2003
This lithograph features Hubble Space Telescope images and includes text that describes and explains the images. The images provide motivation for students to explore and formulate questions.

core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Nighttime Atomic Hydrogen Abundance Retrieved From SCIAMACHY Hydroxyl Airglow Measurements in the Mesopause Region

open access: yesGeophysical Research Letters
Atomic hydrogen (H) is crucial for understanding photochemistry and the energy budget in the mesopause region. However, there is still no consensus on the H abundance in this region.
Xiaolin Wu   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Two‐Dimensional Motions of Diffuse Auroral Patches Under Upstream Dynamic Pressure Enhancements of the Bow Shock

open access: yesGeophysical Research Letters
In this study, we identified 51 dayside diffuse auroral patches and examined their two‐dimensional evolutions by using the Time History of Events and Macroscale Interactions during Substorms probes and the ground‐based all‐sky imager at the South Pole ...
Xinyu Xu   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Tracking system analytic calibration activities for the Mariner Mars 1969 mission [PDF]

open access: yes
Calibration activity of Deep Space Network in support of Mars encounter phase of Mariner Mars 1969 ...
Chao, C. C.   +7 more
core   +1 more source

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