Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Relationship between Children's Independent Activities and the Built Environment of Outdoor Activity Space in Residential Neighborhoods: A Case Study of Nanjing. [PDF]
Zhou Y, Wang M, Lin S, Qian C.
europepmc +1 more source
1 page Provider Notes:Attached are the draft lesson plan and professional interview sheet. I have corresponded with Yong about the resource list. It may be done on Friday, too.
openaire +2 more sources
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Multiwavelength Observations for a Double-decker Filament Channel in AR 13102
We present the observational evidence of the existence of a double-decker filament channel (FC) by using observations in extreme ultraviolet and H α wavelengths.
Yin Zhang +10 more
doaj +1 more source
Exploring factors affecting individual GPS-based activity space and how researcher-defined food environments represent activity space, exposure and use of food outlets. [PDF]
Marwa WL +4 more
europepmc +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
GPS-based activity space exposure to greenness and walkability is associated with increased accelerometer-based physical activity. [PDF]
Marquet O +8 more
europepmc +1 more source
Single Potential Analysis of Cavernous Electric Activity (SPACE) -experiences and Refinements [PDF]
Merckx, L., Stief, Christian Georg
core +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source

