Results 151 to 160 of about 4,049,670 (304)

Effects of Children's Outdoor Physical Activity in the Urban Neighborhood Activity Space Environment. [PDF]

Front Public Health, 2021
Bao Y, Gao M, Luo D, Zhou X.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Spectral Evolution of Pickup Ions across Interplanetary Shocks in the Outer Heliosphere: Observational Constraints and Transport Simulations

The Astrophysical Journal Letters
Pickup ions (PUIs) often experience acceleration and heating as they traverse interplanetary shocks, leading to the formation of a distinct suprathermal tail in their energy spectra downstream of the shock.
Weining Wang, Jiansen He, Die Duan, Zhongwei Yang, Linghua Wang, Hui Li   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Community transmission of multidrug-resistant tuberculosis is associated with activity space overlap in Lima, Peru. [PDF]

BMC Infect Dis, 2021
Bui DP, Chandran SS, Oren E, Brown HE, Harris RB, Knight GM, Grandjean L.   +6 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Mapping Mobility: Utilizing Local-Knowledge-Derived Activity Space to Estimate Exposure to Ambient Air Pollution among Individuals Experiencing Unsheltered Homelessness. [PDF]

Int J Environ Res Public Health, 2022
MacMurdo MG, Mulloy KB, Culver DA, Felix CW, Curtis AJ, Ajayakumar J, Curtis J.   +6 more
europepmc   +1 more source

Space-Time Human Behaviour and Models of Locomotion: the Case of Students in the City of Volos, Greece [PDF]

The problem of space-time human behaviour is currently a very active subject of research in the geography and transport literature. The main objective of this study is the investigation of the factors that configure the dynamics of in-the-city individual
Fotini Moustou, Yorgos Photis
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Association between physical activity and activity space in different farming seasons among rural Lao PDR residents. [PDF]

Trop Med Health, 2021
Jiang H, Lin L, Yonto DA, Pongvongsa T, Kounnavong S, Moji K.   +5 more
europepmc   +1 more source