Results 51 to 60 of about 16,937,312 (352)

Multi‐Technique Study of the Thermospheric Wind Responses to the November 3–4, 2021 Storm

Space Weather
The responses of thermospheric winds at mid and low latitudes to the intense geomagnetic storm of November 3–4, 2021, are examined using multi‐technique observations and simulations with the Thermosphere Ionosphere Electrodynamics General Circulation ...
Xinmiao Xia, Guoying Jiang, Xiaolong Wei, Yajun Zhu, Jiyao Xu, Wei Yuan, Robert B. Kerr, Tulsi Thapa   +7 more
doaj   +1 more source

Space Activity Regulatory Matters of Space Law

Advanced Space Law, 2020
This article studies the issues of international space law and analyses the reasons for its occurrence. At the moment, space law actively develops, and space exploration has become increasingly popular and demanded. Nevertheless, this field’s legal regulations were drawn up in the mid-20th century and are now partly obsolete. Moreover, the set of space-
Andrey Ivanishchuk, Maria Markina
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Development of the Chinese Dual Auroral Radar Network and Preliminary Results

Space Weather
Led by the National Space Science Center of the Chinese Academy of Sciences, we have built a Chinese dual auroral radar network in northern China, which is called the CN‐DARN.
Jiaojiao Zhang, Ailan Lan, Jingye Yan, Xiang Deng, Wei Wang, Hang Li, Lingchen Sun, Ying Nan, Xiaochao Song, Chi Wang   +9 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The New Geomagnetic Monitoring Network in China: Insights From the 2024 Mother's Day Superstorm

Space Weather
China has established a ground‐based network system, that is the Chinese Meridian Project (CMP), to continuously monitor the geomagnetic field. The superstorm in May 2024 was analyzed using the CMP data.
Jing Wang, Yue Yan, Bingxian Luo, Chunming Liu, Hui Li, Jiaojiao Zhang, Yanhong Chen, Chen Wu, Zihan Wu, Ziqian Liu, Xin Wang, Ercha Aa, Xianzhi Ao   +12 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Assimilation of ICON/MIGHTI Wind Profiles into a Coupled Thermosphere/Ionosphere Model Using Ensemble Square Root Filter

Remote Sensing
Precise characterization of the thermospheric neutral wind is essential for comprehending the dynamic interactions within the ionosphere-thermosphere system, as evidenced by the development of models like HWM and the need for localized data.
Meng Zhang, Xiong Hu, Yanan Zhang, Zhaoai Yan, Hongyu Liang, Junfeng Yang, Cunying Xiao, Cui Tu   +7 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source