Results 91 to 100 of about 3,931,453 (288)

Series expansion for a stochastic sandpile

open access: yes, 2003
Using operator algebra, we extend the series for the activity density in a one-dimensional stochastic sandpile with fixed particle density p, the first terms of which were obtained via perturbation theory [R. Dickman and R. Vidigal, J. Phys.
  +23 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Induced starburst and nuclear activity: Faith, facts, and theory [PDF]

open access: yes
The problem of the origin of starburst and nuclear (nonstellar) activity in galaxies is reviewed. A physical understanding of the mechanism(s) that induce both types of activity requires one to address the following issues: (1) what is the source of fuel
Shlosman, Isaac
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Aging: The Two Faces of Janus in Digital Inclusion?

open access: yesInternational Journal of Communication, 2021
Does aging present the two faces of Janus when it comes to digital inclusion, influencing older people’s digital inclusion in some cases, but not in others?
Panayiota Tsatsou
doaj  

Energy Expenditure and Intensity of Interactive Video Dance Games according to Health Recommendations

open access: yesCentral European Journal of Sport Sciences and Medicine, 2018
Backround: The aim of this study was the assessment of energy expenditure (EE) and the intensity of physical activity (PA) of adult women during the interactive dance video game (IDVG) Dance Central on Xbox 360 Kinect in the context of health ...
Jacek Polechoński   +5 more
doaj   +1 more source

Shocking the Crowd: The Effect of Censorship Shocks on Chinese Wikipedia

open access: yes, 2017
Collaborative crowdsourcing has become a popular approach to organizing work across the globe. Being global also means being vulnerable to shocks -- unforeseen events that disrupt crowds -- that originate from any country.
Budak, Ceren   +4 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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