Results 91 to 100 of about 603,389 (218)

Green Sourcing: Supplier Assessment and Selection Practices across Industries

Logistics
Background: Over the last years, the assessment and selection of suppliers, based on the environmental performance of their products/services and their operations, has reached paramount importance and attracted the interest of many researchers and ...
Emmanuel D. Adamides, Yannis Mouzakitis
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Developing Learning Technology Professionals in the Scholarship of Teaching and Learning (SoTL): Insights from a Cross-Institutional Mentor Scholar Scheme

Trends in Higher Education
Debates are taking place in the higher education literature regarding the changing roles of learning technology professionals and their contributions to the scholarship of teaching and learning (SoTL).
Denise Sweeney, Jessica Humphreys, Tünde Varga-Atkins, Brett Bligh, Jim Turner   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Balancing innovation and mentorship in postgraduate supervision through activity theory and artificial intelligence

Educational Technology Quarterly
This study presents a systematic literature review that maps the emerging role of Artificial Intelligence (AI) in postgraduate research supervision.
Gardner Mwansa, Matipa Ricky Ngandu, Mushimbei Mwilima Mwansa   +2 more
doaj   +1 more source

Current research trends on cognition, integrative complexity, and decision-making: a systematic literature review using activity theory and neuroscience. [PDF]

Front Psychol, 2023
Molina I, Molina-Perez E, Sobrino F, Tellez-Rojas MA, Zamora-Maldonado HC, Plaza-Ferreira M, Orozco Y, Espinoza-Juarez V, Serra-Barragán L, De Unanue A.   +9 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Between college and work in the Further Education and Training College sector

South African Journal of Education, 2015
Students studying Civil Engineering (CE) at the Further Education and Training (FET) colleges spend periods of time in the classroom and workshop as well as in the workplace during experiential learning.
James Garraway, Joseph Bronkhorst, Sharman Wickham   +2 more
doaj  

Using cultural historical activity theory to reflect on the sociocultural complexities in OSCE examiners' judgements. [PDF]

Adv Health Sci Educ Theory Pract, 2023
Wong WYA, Thistlethwaite J, Moni K, Roberts C.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source