Results 161 to 170 of about 11,976,431 (285)

Drivers and Outcomes of Engagement in Non-Formal Special Interest Groups Among Japanese Emergency Physicians: An Activity Theory Analysis. [PDF]

AEM Educ Train
Kawaguchi T, Nomura O, Hayakawa K, Fujitani S, Saiki T.   +4 more
europepmc   +1 more source

Linking Activity Theory Within User-Centered Design: Novel Framework to Inform Design and Evaluation of Adverse Drug Reaction Reporting Systems in Pharmacy. [PDF]

JMIR Hum Factors, 2023
Fossouo Tagne J, Yakob RA, Mcdonald R, Wickramasinghe N.   +3 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Engineering Design Strategies for Boosting Photocatalytic Activity: Theory-to-Data-Driven Perspective. [PDF]

Materials (Basel)
Pech-Rodríguez WJ, Şahin NE, Suarez-Velázquez GG.   +2 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

The use of IT-safety and coping measures against cybercrimes among older adults in Hong Kong: an application of cyber routine activity theory. [PDF]

Front Sociol
Lam G, Lau BH, Tsang CK, Kwok AP, Shum EN.   +4 more
europepmc   +1 more source

Game-Based Learning for Learners With Disabilities-What Is Next? A Systematic Literature Review From the Activity Theory Perspective. [PDF]

Front Psychol, 2021
Tlili A, Denden M, Duan A, Padilla-Zea N, Huang R, Sun T, Burgos D.   +6 more
europepmc   +1 more source

The object of activity: Making sense of the sense-maker

, 2005
The concept of “the object of activity” plays a key role in current research based on activity theory. However, the usefulness of this concept is somewhat undermined by the fact that a number of problems related to its meaning and the context of use ...
Kaptelinin, Victor,
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The influence of leadership on stakeholder involvement in the digitalisation of the UK healthcare sector: An activity theory perspective. [PDF]

Digit Health
Hwabamungu B, Shepherd P.
europepmc   +1 more source