Results 51 to 60 of about 3,944,530 (288)

Activity theory: A framework for analysing intercultural academic activity [PDF]

open access: yes, 2010
This article suggests that Activity Theory (AT) can be applied as a holistic framework to analyse the complex sociocultural issues that arise when academics wish to engage in collaborative activity across institutional and cultural boundaries.
Barnard, Roger
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Cultural-Historical Interpretation of Resilience: the implications for practice

open access: yesOutlines, 2007
Recent attempts at preventing the social exclusion of vulnerable children in England have been driven by notions of resilience which centre primarily on changing children so that they may be better able to cope with adversity.
Anne Edwards, Apostol Apostolov
doaj  

Systemic Tensions in the MOOC Design Cycle: An Activity Systems Analysis upon Implementing edX for Latin America and the Caribbean

open access: yesOpen Praxis, 2021
This report presents the activity systems analysis of the general MOOC design process adopted by a multidisciplinary team for delivering edX courses to Latin America and the Caribbean (LAC).
Fabián Freire
doaj  

Applying the ‘Social Turn’ in writing scholarship to perspectives on writing self-efficacy

open access: yesJournal of Learning Development in Higher Education, 2019
The aim of this paper is to explore the fit between the cognitive concept of writing self-efficacy and a socially constructed epistemology of writing.
Kim M. Mitchell   +2 more
doaj   +1 more source

Activity controls fragility: A Random First Order Transition Theory for an active glass

open access: yes, 2017
How does nonequilibrium activity modify the approach to a glass? This is an important question, since many experiments reveal the near-glassy nature of the cell interior, remodelled by activity.
Bhuyan, Pranab Jyoti   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Assistive Technologies: Companion or Controller? – Appropriation Instead of Instruction [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2020
Assistive digital technologies support employees in coping with complex activities by providing the necessary infor-mation directly related to the work task and according to the individual requirements. On the one hand, they have the potential to relieve
Tina Haase   +3 more
doaj  

Symplectic spectral geometry of semiclassical operators [PDF]

open access: yes, 2013
In the past decade there has been a flurry of activity at the intersection of spectral theory and symplectic geometry. In this paper we review recent results on semiclassical spectral theory for commuting Berezin-Toeplitz and h-pseudodifferential ...
Pelayo, Álvaro
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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