Results 31 to 40 of about 183,316 (279)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Actor Network Theory and adult education [PDF]
, 2015 The things and objects that help to enact and animate everyday work and learning practices are often ignored, dismissed or subordinated. Surfacing the materialities of practices is one appeal of theoretical perspectives such as Actor Network Theory (ANT).
Thompson, Terrie Lynn
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Understanding Strategy For E-Government Development Using Actor-Network Theory [PDF]
, 2012 The potential benefits of e-government are not easily manifested due to its high implementation failures. These failures partly come from inappropriate assumptions used to conceptualize its nature and implement it as a socio-technical entity.
Johanes Eka, Priyatma
core
Nordic Journal of Science and Technology Studies, 2014 This special issue of the Nordic Journal of Science and Technology Studies is interested in how nature, in different versions and forms, is invited into our studies, analyses, and stories. How is it that we “write nature”? How is it that we provide space
Kristin Asdal, Gro Birgit Ween
doaj
Computerization of primary health care in Brazil: the network of actors
Revista Brasileira de Enfermagem, 2019 Objective: To analyze the network of human and non-human actors involved in the computerization of primary health care in the Brazilian federal government.
Ricardo Bezerra Cavalcante +5 more
doaj +1 more source
Georg Brandes as an Actor Narrating a Story about Poland
Acta Universitatis Carolinae Philologica, 2023 The aim of the article is to investigate Brandes’s impact on the Poles’ self-image and to explain how he became an actor in an internal Polish network of relationships. Three aspects have been analysed with regard to this aim: the reception of Brandes in
Sylwia Izabela Schab
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Revista Crítica de Ciências Sociais, 2020 This article focuses on the need for a new theoretical and conceptual problematization of community-based tourism or community tourism (CBT) in Brazil, exploring the actor-network theory as a possible analytical tool in this direction.
Edilaine Albertino de Moraes +3 more
doaj +1 more source
A midrange theory of local cross-sector action based on the actor-network theory
SSM: Qualitative Research in Health, 2022 Given the value of cross-sector collaborations in solving complex societal problems, experts are now recommending that research focus on documenting process–effect linkages.
Angèle Bilodeau +5 more
doaj +1 more source