Results 51 to 60 of about 10,163,458 (288)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A midrange theory of local cross-sector action based on the actor-network theory

open access: yesSSM: Qualitative Research in Health, 2022
Given the value of cross-sector collaborations in solving complex societal problems, experts are now recommending that research focus on documenting process–effect linkages.
Angèle Bilodeau   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Combining Luhmann and Actor-Network Theory to see Farm Enterprises as Self-organizing Systems [PDF]

open access: yes, 2003
From a rural, sociological point of view no social theories have so far been able to grasp the ontological complexity and special character of a farm enterprise as an entity in a really satisfying way.
Noe, Egon, Alrøe, Hugo Fjelsted
core   +1 more source

Development of a successful microfinancing system: Actor-network theory perspective

open access: yesManagement : Journal of Contemporary Management Issues, 2019
The article aims to answer the following research question: “How were actors mobilized to form a network for promoting microfinancing system in a transforming country?”.
Halina Waniak-Michalak, Jan Michalak
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Combining Luhmann and Actor-Network Theory to see Farm Enterprises as Self-organizing Systems [PDF]

open access: yes, 2006
From a rural, sociological point of view no social theories have so far been able to grasp the ontological complexity and special character of a farm enterprise as an entity in a really satisfying way.
Noe, Egon, Alrøe, Hugo Fjelsted
core   +1 more source

Turismo de base comunitária à luz da teoria ator-rede: novos caminhos investigativos no contexto brasileiro

open access: yesRevista Crítica de Ciências Sociais, 2020
This article focuses on the need for a new theoretical and conceptual problematization of community-based tourism or community tourism (CBT) in Brazil, exploring the actor-network theory as a possible analytical tool in this direction.
Edilaine Albertino de Moraes   +3 more
doaj   +1 more source

Georg Brandes as an Actor Narrating a Story about Poland

open access: yesActa Universitatis Carolinae Philologica, 2023
The aim of the article is to investigate Brandes’s impact on the Poles’ self-image and to explain how he became an actor in an internal Polish network of relationships. Three aspects have been analysed with regard to this aim: the reception of Brandes in
Sylwia Izabela Schab
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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