Results 71 to 80 of about 183,316 (279)

Using actor-network theory to reveal strategy processes in design firms [PDF]

open access: yes, 2017
In this paper we illustrate the utility of actor-network theory (ANT) as a methodological approach to understand the effect of the eclectic characteristics of design firms on their strategy development processes.
Rieple, A., van den Broek, A.
core  

The internet, E-commerce and older people: an actor-network approach to researching reasons for adoption and use

open access: yes, 2003
Many older people are discovering the Internet, and some are also making good use of electronic commerce and all that goes with it. Others, however, are not adopting these technologies.
Tatnall, Arthur, Lepa, Jerzy
core   +1 more source

Market devices and structural dependency: The origins and development of ‘dark pools’

open access: yesFinance and Society, 2019
‘Dark pools’ are private, electronic share-trading systems in which participants cannot see each other's buy and sell orders. This article shows that the development of these material ‘market devices’ was strongly shaped by the structural dependency of ...
Donald MacKenzie
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The use of Actor-Network Theory and a Practice-Based Approach to understand online community participation [PDF]

open access: yes, 2013
Participation in online communities is problematic. Take up of community technologies is often patchy and subject to resistance, particularly in organisational settings.
Rivera, Gibran
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Sociological theories contributions to the ontological question. The cases of Luhmann, Habermas y Latour

open access: yesRevista de Filosofia, 2016
In this paper are discussed the contributions of the contemporary sociological theory to the philosophical and scientical question of Ontology, for this purpose are compared the ontological assumptions elaborated for the General Social Systems Theory by ...
Sergio Pignuoli Ocampo
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Combining Luhmann and Actor-Network Theory to see Farm Enterprises as Self-organizing Systems

open access: yes, 2006
From a rural, sociological point of view no social theories have so far been able to grasp the ontological complexity and special character of a farm enterprise as an entity in a really satisfying way.
Noe, Egon, Alrøe, Hugo Fjelsted
core  

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