Results 81 to 90 of about 359,514 (275)
Explanation and trust: what to tell the user in security and AI? [PDF]
, 2010 There is a common problem in artificial intelligence (AI) and information security. In AI, an expert system needs to be able to justify and explain a decision to the user.
Pieters, Wolter
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Toward an analytical and methodological understanding of actor-network theory [PDF]
, 2015 Actor-Network theory (ANT) is well developed within social studies of science and technology. The last two decades have seen an increasing awareness and interest in ANT within the social sciences and it has increasingly been invoked to theorise the role ...
Jackson, Sharon
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Place Construction and Urban Social Transformation : An Actor Network Theory Analysis for Creative Kampong Phenomena in Bandung [PDF]
, 2013 How built environment plays role in social transformation?This question is one concern of social-constructivism approach in study of place. Place construction studies focus on space that socially constructed and social that spatially constructed.
Frans Prasetyo
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Market devices and structural dependency: The origins and development of ‘dark pools’
Finance and Society, 2019 ‘Dark pools’ are private, electronic share-trading systems in which participants cannot see each other's buy and sell orders. This article shows that the development of these material ‘market devices’ was strongly shaped by the structural dependency of ...
Donald MacKenzie
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The Politics of "Actor-Network Theory" [PDF]
This text discusses controversies surrounding theoretical, practical, and political implications of "actor-network theory" ("ANT"). Since its inception around 1980, "ANT" has been applied in an immense number of empirical studies, both within and outside
Berker, Thomas
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The Safety Net as a Network [PDF]
, 2007 The lack of a coherent understanding of what is meant by the American safety net made it difficult to have a meaningful discourse on the current condition. This paper proposes an alternative formulation of the social safety net based in network theory to
Liu, Helen K.
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
French theories in IS : an exploratory study on ICIS, AMCIS and MISQ. [PDF]
French theories; Information Systems Research; Actor-network theory;
Monod, Emmanuel
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