Results 91 to 100 of about 2,042,802 (273)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Inercias y tranformaciones en las relaciones laborales del Uruguay
This work intends to analyze the evolution of the labor relations in Uruguay, at the cornerstone of the productive restructuring processes that began to be developed starting from the constitution of regional markets in the Southern Cone.
Francisco Pucci
doaj +1 more source
Transfer agents and global networks in the 'transnationalization' of policy [PDF]
This paper focuses on the role of international actors in policy/ knowledge transfer processes to suggest a dynamic for the transnationalization of policy results.
Stone, Diane
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The first experiments in business theatre aimed at solving internal “dysfunctions” in companies were launched in France in the late 1980s. However, these plays were performed by professional actors and actresses who played fictitious characters related ...
Cécile Ferro, Marie Buscatto
doaj +1 more source
Nonrational Actors and Financial Market Behavior [PDF]
The insights of descriptive decision theorists and psychologists, we believe, have much to contribute to our understanding of financial market macrophenomena.
Darryll Hendricks +2 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The nexus between hybrid warfare and contemporary terrorism [PDF]
The theme of the paper is the examination of the depth of the connection between terrorism and hybrid warfare. Regardless of the current disagreements among theorists about whether "hybrid war" is a modern form of warfare or "an old phenomenon in new ...
Đorđević Marko, Miljković Milan
doaj +1 more source

