Results 101 to 110 of about 5,293,771 (310)

“Spiritual Gymnastics”: Reflections on Michel Foucault’s On the Government of the Living 1980 Collège de France lectures

open access: yesFoucault Studies, 2015
This review locates the 1980 lectures within the context of the wider discussions of Foucault and religion; highlighting the influence of George Dumézil on the comparative and structural analysis.
Jeremy Carrette
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Marcion and Luke-Acts: a defining struggle [PDF]

open access: yes, 2008
Title: Marcion and Luke-Acts: a defining struggle. Author: Tyson, Joseph B Marcion and Luke-Acts xiv, 191 p.
Cole-Arnal, Oscar
core   +1 more source

Act of violence - act of love

open access: yes, 2012
Eine Adoption bedeutet meist den Bruch mit der leiblichen Familie – zu verstehen als ein „Akt der Gewalt“ – und die Inkorporation in ein neues Familiennetzwerk – einen „Akt der Liebe“. Kinder zu bekommen wird in unserer Gesellschaft als wichtiger Teil des Lebens gesehen und trotz Fortschritten in der Reproduktionsmedizin, bleibt die Zahl international ...
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Criação, Cristãos e “Environmental Stewardship”

open access: yesFronteiras: Journal of Social, Technological and Environmental Science, 2015
Este artigo se fundamenta numa discussão teórica entre religião e ambientalismo. O texto tem por finalidade apresentar um debate entre os princípios do cristianismo e as discussões teóricas que fundamental a visão ambientalista nos dias atuais. O caminho
Ken Gnanakan
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Awareness of Medico-legal Legislations and Ethics among Audiologists and Speech–language Pathologists: A Preliminary Educational Intervention Study

open access: yesJournal of Indian Speech Language & Hearing Association
Introduction: Rehabilitation professionals are experts who work for various rehabilitation services, including Audiologists and Speech-Language Pathologists (ASLPs). In professional practice, understanding the interplay between ethics and laws is crucial
Swathi Chinnasamy   +2 more
doaj   +1 more source

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