Results 111 to 120 of about 5,293,771 (310)
ACTS in Need: Automatic Configuration Tuning with Scalability Guarantees
To support the variety of Big Data use cases, many Big Data related systems expose a large number of user-specifiable configuration parameters. Highlighted in our experiments, a MySQL deployment with well-tuned configuration parameters achieves a peak ...
Bao, Yungang +4 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Banking system of the USA, Germany and Japan: comparative analysis
In article the comparative analysis of formation and development of a banking system of the USA, Germany, Japan is carried out, are revealed strong and weaknesses of each of bank systems, measures for their further development and improvement are offered.
A. I. Vinogradov
doaj
ACTS propagation program [PDF]
The Advanced Communications Technology Satellite (ACTS) Propagation Program is organized to fulfill certain needs and requirements of the ACTS community.
Davarian, Faramaz
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Why Proximity Matters for the Concept of Supererogation [PDF]
The concept of supererogation is strictly correlated with duty, since its peculiar value is defined by acts that go beyond our regular obligations.
Grigoletto, Simone
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Can you have bullying without a bully? [PDF]
When I write my name on a piece of paper, the actions I perform can constitute a variety of different acts. For example, depending on the piece of paper on which I write, they might represent the act of making a contract or, if the piece of paper is a ...
FAIRBAIRN, G
core

