ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Formulation of the actual state principle for a physical system [PDF]
Introduction. The article briefly discusses the state of scientific research in the field of mathematical modeling of physical systems with distributed parameters. Mathematical modeling in elasticity theory. The initial boundary value problem of linear
Boris V. Gusev, Vasily V. Saurin
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Evaluation of acceptance of information systems in state university with theory of planned behavior and theory of acceptance model approaches [PDF]
Development of information systems in state universities, is needed in order to support more effective and efficient performance. This research was conducted to evaluate the factors that influence the intensity and behavior of users when using user ...
S. Martono +3 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The actual state and problems in neurology training at hospital
To evaluate postgraduate neurological education, a questionnaire-based survey regarding junior and senior doctor-in-training and the Board Certification Examination in Neurology was carried out on the training supervisors of 690 insitutes, excluding 80 university hospitals. The institutes included 243 teaching hospitals, 326 semi-teaching hospitals and
Fukutake, Toshio +8 more
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
ANALYSIS OF THE ACTUAL STATE LUBRICANT TO RESOURCE ELEMENTS CRUSHING AND GRINDING MACHINERY
The probabilistic nature of resource allocation units, assembly units and parts of machines and equipment, including crushing and grinding, detects the presence of certain reserves in the improvement of preventive work the system for maintenance and ...
V. N. Kuznetsova, Ya. V. Yarmovich
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The actual state of the geodetic and cartographic resources and legislation in Poland
Official data, including national geodetic and cartographic resources, are integrated in a spatial reference system. This study outlines national resources in Poland as an important part of the spatial information infrastructure in the European Community.
Doskocz Adam
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

