Results 41 to 50 of about 862,257 (255)

ACTUAL ISSUES OF THE STATE LANGUAGE TEACHING

open access: yesJOURNAL OF LOOK TO THE PAST, 2021
This article analyzes the current issues of teaching the state language and solutions of teaching problems. Especially in the system of higher education, the meaning of scientific methodsand terms is revealed that bring students closer to the language of their specialization.
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

State Contract and Value Added Tax: Actual Issues of Judicial Practices

open access: yesУправленческое консультирование, 2018
The article is devoted to the legal analysis of legislation and judicial practices in the field of public procurement. Over recent years increasing attention is paid to relations in the sphere of procurement of goods, performance of works, rendering of ...
Alina Vladimirovna Kostyukova   +1 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Establishing the need to model the actual state of stress along rock bolts

open access: yesInternational Journal of Mining Science and Technology, 2020
Proper design of rock bolt support in underground mines is critical to avoid incidents, accidents and loss of production. The traditional design approach only considers the axial (tensile) capacity and this is clearly not the situation in situ, where a ...
Prasoon Singh   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Bifocal contact lenses: History, types, characteristics, and actual state and problems

open access: yesClinical Ophthalmology, 2008
Hiroshi Toshida, Kozo Takahashi, Kazushige Sado, Atsushi Kanai, Akira MurakamiDepartment of Ophthalmology, Juntendo University School of Medicine, Tokyo, JapanAbstract: Since people who wear contact lenses (CL) often continue using CL even when they ...
Hiroshi Toshida   +4 more
doaj  

Actual state of knowledge in the field of Supply Chain Management

open access: yesMATEC Web of Conferences, 2017
This paper aims to analyse the actual state of research in the field of supply chain management and to identify eventual gaps of knowledge and potential research directions in the field concerned.
Dumitrascu Oana, Hila Constantin Manuel
doaj   +1 more source

Sustainable development, eco-tourism carrying capacity and fuzzy algorithm-a study on Kanas in Belt and Road

open access: yesScientific Reports, 2023
In this paper, the method of fuzzy pattern recognition is adopted in more precisely evaluating the actual state of eco-tourism development regarding a given tourist destination in comparison with the three standard patterns (saturated/optimal/deficient ...
Kui Yu, Han Gao
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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