Results 41 to 50 of about 19,877,463 (302)
ACTUAL STATE OF DOLLAR DIPLOMACY IN AMERICAN ECONOMIC POLICY [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2011 As it is commonly known, the U.S. economy is the most powerful economy of the world, despite the indicator or the system of indicators that can be taken into account in the analysis. As we said, the twentieth century was a century of America. Future
Dorel Dumitru CHIRIŢESCU +1 more
doaj
State Contract and Value Added Tax: Actual Issues of Judicial Practices
Управленческое консультирование, 2018 The article is devoted to the legal analysis of legislation and judicial practices in the field of public procurement. Over recent years increasing attention is paid to relations in the sphere of procurement of goods, performance of works, rendering of ...
Alina Vladimirovna Kostyukova +1 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Establishing the need to model the actual state of stress along rock bolts
International Journal of Mining Science and Technology, 2020 Proper design of rock bolt support in underground mines is critical to avoid incidents, accidents and loss of production. The traditional design approach only considers the axial (tensile) capacity and this is clearly not the situation in situ, where a ...
Prasoon Singh +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Bifocal contact lenses: History, types, characteristics, and actual state and problems
Clinical Ophthalmology, 2008 Hiroshi Toshida, Kozo Takahashi, Kazushige Sado, Atsushi Kanai, Akira MurakamiDepartment of Ophthalmology, Juntendo University School of Medicine, Tokyo, JapanAbstract: Since people who wear contact lenses (CL) often continue using CL even when they ...
Hiroshi Toshida +4 more
doaj
Scientific Reports, 2023 In this paper, the method of fuzzy pattern recognition is adopted in more precisely evaluating the actual state of eco-tourism development regarding a given tourist destination in comparison with the three standard patterns (saturated/optimal/deficient ...
Kui Yu, Han Gao
doaj +1 more source