Results 61 to 70 of about 147,627 (276)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Beyond information extraction: The role of ontology in military report processing [PDF]

, 2004
Information extraction tools like SMES transform natural language into formal representation, e.g. into feature structures. Doing so, these tools exploit and apply linguistic knowledge about the syntactic and morphological regularities of the language ...
Frey, Miloslaw, Schade, Dr. Ulrich
core  

Actualism, Serious Actualism, and Quantified Modal Logic

Notre Dame Journal of Formal Logic, 2018
The paper navigates in the waters between metaphysical doctrine and formal logical representation. The goal is to build a first-order modal logic that accommodates both ``actualism'' (the view there are no merely possible things, that is, things that do not exist but have some alternative kind of being) and ``serious actualism'' (that all sentences ...
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Word-formation activation of Japanese borrowings in the modern Russian language

Неофилология, 2020
Problematics of the work is connected with the study of the borrowing process, which, due to the process of globalization taking place at all Russian society’s levels of life, is highlighted as a factor of modern language development.
E. V. Senko, L. V. Tsakhilova
doaj   +1 more source

Eksperimentasi Model Pembelajaran Kooperatif Tipe Numbered Heads Together (Nht) Dan Roundtable Terhadap Prestasi Belajar Matematika Ditinjau Dari Aktualisasi Diri Siswa SMP Negeri Di Kabupaten Magelang [PDF]

, 2013
The aim of this research was to determine the effects of learning models on mathematics achievement viewed from the students' self-actualization. The learning models compared were conventional model, cooperative learning model NHT type and RoundTable ...
Ingkansari, A. R. (Agnes), Mardiyana, M. (Mardiyana), Usodo, B. (Budi)   +2 more
core  

Digital play and the actualisation of the consumer imagination [PDF]

, 2007
In this article, the authors consider emerging consumer practices in digital virtual spaces. Building on constructions of consumer behavior as both a sense-making activity and a resource for the construction of daydreams, as well as anthropological ...
Denegri-Knott, Janice, Molesworth, Mike
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The Conscious Organization: Prospects for a Self-Actualized Workforce [PDF]

, 2012
Values-based leadership is not something that is readily attainable without an individual and collective commitment to a lifelong course of self-evaluation.
Renesch, John
core   +2 more sources

Cooperation and defection in ghetto

, 2005
We consider ghetto as a community of people ruled against their will by an external power. Members of the community feel that their laws are broken. However, attempts to leave ghetto makes their situation worse.
Aydiner E., Hannerz U., KRZYSZTOF KUŁAKOWSKI, Kȩpiński A., Malarz K., Marshall G., Maslow A. H., Novotny M. A., Ron J., Smelser N. J., Straffin P. D., van Kampen N. G., Weidlich W.   +12 more
core   +1 more source