Results 41 to 50 of about 2,125 (255)
Del "scriptor" al "publicus notarius" : los escribanos de Madrid en el siglo XIII
Espacio, Tiempo y Forma. Serie III, Historia Medieval, 2003 Estudio diplomático y jurídicoinstitucional de las escribanías de Madrid en el siglo XIII. Se analiza su evolución desde los primeros "Scriptores» prenotariales conocidos, clérigos y laicos de libre profesión, documentados hasta 1260, hasta la ...
María Teresa Carrasco Lazareno
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Divulgação de trabalho: considerações sobre os doze anos do caderno de estudos
Revista Contabilidade & Finanças, 2002 Este artigo tem o propósito de apresentar uma avaliação do periódico corrente Caderno de Estudos, atual Revista Contabilidade & Finanças - USP, publicado pela Fundação Instituto de Pesquisas Contábeis, Atuariais e Financeiras -FIPECAFI, entidade de apoio
Gilberto de Andrade Martins
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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THE ROLE AND SIGNIFICANCE OF THE CREDIBILITY THEORY IN ACTUARIAL PRACTICE
Pravo, 2014 Actuarial science is based on the use of financial and statistical models and depends on the practical framework, starting from the operation of the insurance market through the accounting system and the available data.
Nataša Papić Blagojević +1 more
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Modelling Unobserved Heterogeneity in Claim Counts Using Finite Mixture Models
Risks, 2020 When modelling insurance claim count data, the actuary often observes overdispersion and an excess of zeros that may be caused by unobserved heterogeneity.
Lluís Bermúdez +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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