Results 21 to 30 of about 478,633 (337)

P-11 POTENTIALLY HEPATOTOXIC DRUGS ARE STILL BEING PRESCRIBED TO LIVER DISEASE PATIENTS UNDER TERTIARY CARE: IT IS TIME TO SAY ENOUGH

open access: yesAnnals of Hepatology, 2021
Introduction and Aim: Drug-induced liver injury (DILI) manifests as a spectrum of clinical presentations that carries morbidity and mortality. Patients with chronic liver disease (CLD), particularly hospitalized, are at high risk for developing DILI.
Rodrigo Dorelo   +9 more
doaj   +1 more source

Acute-On-Chronic Liver Failure [PDF]

open access: yesClinics in Liver Disease, 2014
The Model for End-Stage Liver Disease (MELD) has been the single best predictor of outcome of the progression of cirrhosis. Acute-on-chronic liver failure (ACLF) has been proposed as an alternative path in the natural history of cirrhosis. ACLF occurs in patients with chronic liver disease and is characterized by a precipitating event, resulting in ...
Sumeet K, Asrani, Jacqueline G, O'Leary
openaire   +2 more sources

Chronic Hepatitis C: Acute Exacerbation and Alanine Aminotransferase Flare

open access: yesViruses, 2023
The hepatitis C virus (HCV) causes acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently, direct-acting antiviral agents (DAAs) against HCV infection can lead to
Tatsuo Kanda   +12 more
doaj   +1 more source

Acute-on-Chronic Liver Failure: Definition, Diagnosis, and Clinical Characteristics [PDF]

open access: yes, 2016
Acute-on-chronic liver failure (ACLF) is a recently recognized syndrome in cirrhosis characterized by acute decompensation (AD), organ failure(s), and high short-term mortality.
Arroyo, V   +9 more
core   +1 more source

Development and validation of a dynamic survival prediction model for patients with acute-on-chronic liver failure

open access: yesJHEP Reports, 2021
Background & Aims: Acute-on-chronic liver failure (ACLF) is usually associated with a precipitating event and results in the failure of other organ systems and high short-term mortality. Current prediction models fail to adequately estimate prognosis
Ben F.J. Goudsmit   +7 more
doaj   +1 more source

Acute-on chronic liver failure

open access: yesJournal of Hepatology, 2012
Acute-on-chronic liver failure (ACLF) is an increasingly recognised entity encompassing an acute deterioration of liver function in patients with cirrhosis, which is usually associated with a precipitating event and results in the failure of one or more organs and high short term mortality.
Jalan, Rajiv   +7 more
openaire   +2 more sources

Determination of HMGB1 in hepatitis B virus-related acute-on-chronic liver failure patients with acute kidney injury: Early prediction and prognostic implications

open access: yesFrontiers in Pharmacology, 2023
Background: Acute kidney injury (AKI) is a frequent complication in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) and is associated with high rates of mortality. We aimed to estimate serum high mobility group protein 1
Yu Liu   +14 more
doaj   +1 more source

Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]

open access: yes, 2017
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania   +21 more
core   +2 more sources

The molecular adsorbent recirculating system as a liver support system. Summary of Mexican experience

open access: yesAnnals of Hepatology, 2014
Aim. The aim of this study was to assess the effects of the molecular absorbent recirculating system (MARS) on patients with acute liver failure (ALF) and liver failure with cirrhosis (AoCLF) as well as in cholestatic patients with intractable pruritus ...
Laura Esthela Cisneros-Garza   +6 more
doaj   +1 more source

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