Results 11 to 20 of about 273,878 (250)

Unbiased clustering of acute-on-chronic liver failure patients using machine learning in a real-world ICU cohort [PDF]

Nature Communications
Acute-on-chronic liver failure is a complex condition with varied definitions, complicating risk stratification and targeted management. We apply unsupervised clustering to data from 1,256 patients with acute-on-chronic liver failure as defined by the ...
Mengyi Zhang, Fanpu Ji, Jian Zu, Yingli He, Tao Chen, Yi Liu, Hirsh D. Trivedi, Ju Dong Yang, Vinay Sundaram, Yuan Wang, Xiaodan Sun, Zhujun Cao, Chun-Ying Wu, Yee Hui Yeo, Rajiv Jalan   +14 more
doaj   +2 more sources

Acute-on-chronic liver failure [PDF]

Clinical Medicine, 2020
Acute-on-chronic liver failure (ACLF) is a recently recognised and defined syndrome seen in patients with liver cirrhosis and carries a high short-term mortality in excess of 15% at 28 days. ACLF is defined by organ failures (OFs) and is distinct from simple 'acute decompensation' (AD) of cirrhosis.
Kumar, R, Mehta, G, Jalan, R
  +11 more sources

Acute on chronic liver failure in cirrhosis [PDF]

Clinical and Molecular Hepatology, 2022
Marta Tonon, Salvatore Piano
doaj   +4 more sources

Acute-on-chronic liver failure [PDF]

The Lancet, 2015
Acute-on-chronic liver failure combines an acute deterioration in liver function in an individual with pre-existing chronic liver disease and hepatic and extrahepatic organ failures, and is associated with substantial short-term mortality. Common precipitants include bacterial and viral infections, alcoholic hepatitis, and surgery, but in more than 40%
William, Bernal, Rajiv, Jalan, Alberto, Quaglia, Kenneth, Simpson, Julia, Wendon, Andrew, Burroughs   +5 more
openaire   +4 more sources

A preliminary experience of plasma exchange in liver failure

Asian Journal of Transfusion Science, 2022
INTRODUCTION: Plasma exchange (PLEX) is one of the experimental modalities of treatment for liver failure. We report our experience of PLEX in patients with acute-(ALF) or acute-on-chronic (ACLF) liver failure.
Himanshu Dandu, Vivek Kumar, Amit Goel, Dheeraj Khetan, Tulika Chandra, Vipin Raj Bharti   +5 more
doaj   +1 more source

Potentially hepatotoxic drugs are still being prescribed to liver disease patients under tertiary care: it is time to say enough

Revista Peruana de Investigación en Salud, 2021
Introduction and aim: Drug-induced liver injury (DILI) manifests as a spectrum of clinical presentations that carries morbidity and mortality. Patients with chronic liver disease (CLD), particularly hospitalized, are at high risk for developing DILI.
Rodrigo Dorelo, Samantha T.A. Barcelos, Magela Barros, Valeria Elustondo, Ysela Y.P. Pérez, Martin Oricchio, Nelson D.S. Uribe, Nelia Hernandez, Dvora Joveleviths, Mario R. Alvares-da-Silva   +9 more
doaj   +1 more source

Hepatitis E virus infection in patients with acute on top of chronic liver diseases [PDF]

Minia Journal of Medical Research, 2020
Introduction: Acute on chronic liver failure (ACLF) characterized mainly by acute deterioration of underlying chronic liver disease. Hepatitis E virus (HEV) was reported as a precipitating event.
Randa Ali, Shereen Gaber, Reem El Sheemy, Magdy Fouad   +3 more
doaj   +1 more source

Acute‐on‐chronic liver failure: Epidemiology, prognosis, and outcome of a multicenter study in Thai population

JGH Open, 2022
Background and Aim Acute‐on‐chronic liver failure (ACLF) leads to multi‐organ failure related to high mortality rates. This study aimed to gather epidemiological data and validate a scoring system to predict mortality in ACLF.
Sakkarin Chirapongsathorn, Tongluk Teerasarntipan, Krit Tipchaichatta, Tanita Suttichaimongkol, Naichaya Chamroonkul, Chalermrat Bunchorntavakul, Sith Siramolpiwat, Siwaporn Chainuvati, Abhasnee Sobhonslidsuk, Apinya Leerapun, Teerha Piratvisuth, Wattana Sukeepaisarnjaroen, Tawesak Tanwandee, Sombat Treeprasertsuk   +13 more
doaj   +1 more source

Liver Support System and Transplant-Free Survival Patients with Liver Failure: An Evidence-Based Case Report

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: The mortality rate in patients with acute liver failure (ALF) and acute on chronic liver failure (ACLF) is still very high. Currently, liver support systems are an alternative therapy in bridging liver transplantation.
Aravinda Pravita, Kresna Adhiatma, Juferdy Kurniawan   +2 more
doaj   +1 more source

P-11 POTENTIALLY HEPATOTOXIC DRUGS ARE STILL BEING PRESCRIBED TO LIVER DISEASE PATIENTS UNDER TERTIARY CARE: IT IS TIME TO SAY ENOUGH

Annals of Hepatology, 2021
Introduction and Aim: Drug-induced liver injury (DILI) manifests as a spectrum of clinical presentations that carries morbidity and mortality. Patients with chronic liver disease (CLD), particularly hospitalized, are at high risk for developing DILI.
Rodrigo Dorelo, Samantha T.A. Barcelos, Magela Barros, Valeria Elustondo, Ysela Y.P. Pérez, Martin Oricchio, Nelson D.S. Uribe, Nelia Hernandez, Dvora Joveleviths, Mário R. Álvares-da-Silva   +9 more
doaj   +1 more source