Results 31 to 40 of about 273,878 (250)
The brain in acute on chronic liver failure [PDF]
Metabolic Brain Disease, 2014 Acute-on-chronic liver failure (ACLF) is a newly defined clinical entity with significant morbidity and mortality (~40-90% at 1 year dependent on need for organ support at presentation). It defines a presentation with acute severe liver injury, often with multiorgan dysfunction, on a background of previously known or unknown cirrhosis.
Wright, G +3 more
openaire +3 more sources
Liver transplantation for acute-on-chronic liver failure from erythropoietic protoporphyria [PDF]
Clinical and Molecular Hepatology, 2012 Erythropoietic protoporphyria (EPP) is an inherited disorder of the heme metabolic pathway that is characterized by accumulation of protoporphyrin in the blood, erythrocytes, and tissues, and cutaneous manifestations of photosensitivity, all resulting ...
Pyoung-Jae Park +9 more
doaj +1 more source
Medicina, 2023 Both the Chronic Liver Failure Consortium (CLIF-C) organ failure score (OFs) and the CLIF-C acute-on-chronic-liver failure (ACLF) score (ACLFs) were developed for risk stratification and to predict mortality in patients with liver cirrhosis and ACLF ...
Michael Nagel +7 more
doaj +1 more source
Acute-on-chronic liver failure in cirrhosis [PDF]
Nature Reviews Disease Primers, 2016 The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium guidelines, which defines this condition as a syndrome that develops in patients with cirrhosis and is ...
Arroyo, Vicente +9 more
openaire +7 more sources
Frailty and Sarcopenia in Acute‐on‐Chronic Liver Failure [PDF]
Hepatology Communications, 2021 In patients with cirrhosis, sarcopenia is a critical reduction in skeletal muscle mass and frailty represents a status of global physical dysfunction caused by under nutrition, muscle wasting, and functional impairment. Both are prevalent conditions in liver transplant candidates and have shown to be independent predictors of adverse outcome.
Lorena Puchades Renau +5 more
openaire +4 more sources
Effect of acute on chronic liver failure over post-transplant survival
Annals of Hepatology, 2023 Introduction and Objectives: Acute-on-chronic liver failure (ACLF) is associated with reduced short-term survival, and liver transplantation is frequently the only therapeutic option.
Carlos Benítez +18 more
doaj +1 more source
PLoS ONE, 2014 IntroductionAcute-on-chronic liver failure is characterized by acute deterioration of liver function in patients with compensated or decompensated, but stable, cirrhosis.
Roland Amathieu +9 more
doaj +1 more source
Plasma Glutamine Concentrations in Liver Failure. [PDF]
PLoS ONE, 2016 Higher than normal plasma glutamine concentration at admission to an intensive care unit is associated with an unfavorable outcome. Very high plasma glutamine levels are sometimes seen in both acute and chronic liver failure.
Gunnel Helling +7 more
doaj +1 more source
Critical Care, 2022 Organ dysfunction or overt failure is a commonplace event in the critically ill affecting up to 70% of patients during their stay in the ICU. The outcome depends on the resolution of impaired organ function, while a domino-like deterioration of organs ...
Aritz Perez Ruiz de Garibay +4 more
doaj +1 more source
Effect of cirrhosis on prognosis in patients with acute-on-chronic liver failure: a systematic review and meta-analysis [PDF]
PeerJBackground Acute-on-chronic liver failure (ACLF) is a prevalent complication among cirrhosis patients, whose high mortality is linked to cirrhosis combined with ACLF. Nevertheless, there is a paucity of systematic reviews.
Chunyang Dong +3 more
doaj +2 more sources