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Chronic Hepatitis C: Acute Exacerbation and Alanine Aminotransferase Flare
The hepatitis C virus (HCV) causes acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently, direct-acting antiviral agents (DAAs) against HCV infection can lead to
Tatsuo Kanda +12 more
doaj +1 more source
Acute-on-Chronic Liver Failure: Definition, Diagnosis, and Clinical Characteristics [PDF]
Acute-on-chronic liver failure (ACLF) is a recently recognized syndrome in cirrhosis characterized by acute decompensation (AD), organ failure(s), and high short-term mortality.
Arroyo, V +9 more
core +1 more source
MARS therapy, the bridging to liver retransplantation-Three cases from the Hungarian liver transplant program [PDF]
Besides orthotopic liver transplantation (OLT) there is no long-term and effective replacement therapy for severe liver failure. Artificial extracorporeal liver supply devices are able to reduce blood toxin levels, but do not replace any synthetic ...
Bacher A. +20 more
core +2 more sources
Aim. The aim of this study was to assess the effects of the molecular absorbent recirculating system (MARS) on patients with acute liver failure (ALF) and liver failure with cirrhosis (AoCLF) as well as in cholestatic patients with intractable pruritus ...
Laura Esthela Cisneros-Garza +6 more
doaj +1 more source
Background & Aims: Acute-on-chronic liver failure (ACLF) is usually associated with a precipitating event and results in the failure of other organ systems and high short-term mortality. Current prediction models fail to adequately estimate prognosis
Ben F.J. Goudsmit +7 more
doaj +1 more source
Background: Acute kidney injury (AKI) is a frequent complication in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) and is associated with high rates of mortality. We aimed to estimate serum high mobility group protein 1
Yu Liu +14 more
doaj +1 more source
Immune dysfunction in cirrhosis. [PDF]
Innate and adaptive immune dysfunction, also referred to as cirrhosis-associated immune dysfunction syndrome, is a major component of cirrhosis, and plays a pivotal role in the pathogenesis of both the acute and chronic worsening of liver function ...
Antal-Szalmás, Péter +3 more
core +1 more source
Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania +21 more
core +2 more sources
Liver transplantation for alcoholic cirrhosis: Long term follow-up and impact of disease recurrence [PDF]
Background. Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse.
Andrea M. DiMartini +71 more
core +2 more sources
Liver Transplantation for Acute on Chronic Liver Failure [PDF]
Acute-on chronic liver failure (ACLF) is defined as acute insult on previous liver disease that causes sudden worsening of liver functions.ACLF is characterized by high incidence of organ failure and prognosis is remarkably worse than patients with cirrhosis. Incidence of organ failures is very high despite best medical care and timely liver transplant
Narendra S. Choudhary +3 more
openaire +2 more sources

