Results 1 to 10 of about 476,540 (289)

Potentially hepatotoxic drugs are still being prescribed to liver disease patients under tertiary care: it is time to say enough

Revista Peruana de Investigación en Salud, 2021
Introduction and aim: Drug-induced liver injury (DILI) manifests as a spectrum of clinical presentations that carries morbidity and mortality. Patients with chronic liver disease (CLD), particularly hospitalized, are at high risk for developing DILI.
Rodrigo Dorelo, Samantha T.A. Barcelos, Magela Barros, Valeria Elustondo, Ysela Y.P. Pérez, Martin Oricchio, Nelson D.S. Uribe, Nelia Hernandez, Dvora Joveleviths, Mario R. Alvares-da-Silva   +9 more
doaj   +1 more source

Liver Support System and Transplant-Free Survival Patients with Liver Failure: An Evidence-Based Case Report

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: The mortality rate in patients with acute liver failure (ALF) and acute on chronic liver failure (ACLF) is still very high. Currently, liver support systems are an alternative therapy in bridging liver transplantation.
Aravinda Pravita, Kresna Adhiatma, Juferdy Kurniawan   +2 more
doaj   +1 more source

Chronic Hepatitis C: Acute Exacerbation and Alanine Aminotransferase Flare

Viruses, 2023
The hepatitis C virus (HCV) causes acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently, direct-acting antiviral agents (DAAs) against HCV infection can lead to
Tatsuo Kanda, Naoki Matsumoto, Tomotaka Ishii, Shuhei Arima, Shinji Shibuya, Masayuki Honda, Reina Sasaki-Tanaka, Ryota Masuzaki, Shini Kanezawa, Tsukasa Nishizawa, Yasuhiro Gon, Masahiro Ogawa, Hirofumi Kogure   +12 more
doaj   +1 more source

Acute-on-Chronic Liver Failure: Definition, Diagnosis, and Clinical Characteristics [PDF]

, 2016
Acute-on-chronic liver failure (ACLF) is a recently recognized syndrome in cirrhosis characterized by acute decompensation (AD), organ failure(s), and high short-term mortality.
Arroyo, V, Fernandez, J, Garcia-Tsao, G, Gines, P, Jalan, R, Kamath, PS, Moreau, R, Nevens, F, Schnabl, B, To, U   +9 more
core   +1 more source

Development and validation of a dynamic survival prediction model for patients with acute-on-chronic liver failure

JHEP Reports, 2021
Background & Aims: Acute-on-chronic liver failure (ACLF) is usually associated with a precipitating event and results in the failure of other organ systems and high short-term mortality. Current prediction models fail to adequately estimate prognosis
Ben F.J. Goudsmit, Andries E. Braat, Maarten E. Tushuizen, Minneke J. Coenraad, Serge Vogelaar, Ian P.J. Alwayn, Bart van Hoek, Hein Putter   +7 more
doaj   +1 more source

MARS therapy, the bridging to liver retransplantation-Three cases from the Hungarian liver transplant program [PDF]

, 2014
Besides orthotopic liver transplantation (OLT) there is no long-term and effective replacement therapy for severe liver failure. Artificial extracorporeal liver supply devices are able to reduce blood toxin levels, but do not replace any synthetic ...
Bacher A., Ding Y.T., Doros A., Evenepoel P., Gaspari R., Hessel F.P., Kantola T., Kantola T., Karvellas C.J., Liu Y.H., Nemes B., Nemes B., Novelli G., Novelli G., Rademacher S., Rifai K., Schiff E.R., Schuller J., Tan H.K., Wang M.M., Wong F.   +20 more
core   +2 more sources

The molecular adsorbent recirculating system as a liver support system. Summary of Mexican experience

Annals of Hepatology, 2014
Aim. The aim of this study was to assess the effects of the molecular absorbent recirculating system (MARS) on patients with acute liver failure (ALF) and liver failure with cirrhosis (AoCLF) as well as in cholestatic patients with intractable pruritus ...
Laura Esthela Cisneros-Garza, Ma. del Rosario Muñoz-Ramírez, Linda Elsa Muñoz-Espinoza, José Antonio Velarde Ruiz Velasco, Rosalba Moreno-Alcántar, Eduardo Marín-López, Nahum Méndez-Sánchez   +6 more
doaj   +1 more source

Determination of HMGB1 in hepatitis B virus-related acute-on-chronic liver failure patients with acute kidney injury: Early prediction and prognostic implications

Frontiers in Pharmacology, 2023
Background: Acute kidney injury (AKI) is a frequent complication in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) and is associated with high rates of mortality. We aimed to estimate serum high mobility group protein 1
Yu Liu, Yu Liu, Wei Yuan, Miao Fang, Hongying Guo, Xin Zhang, Xue Mei, Yuyi Zhang, Longshan Ji, Yating Gao, Jiefei Wang, Zhiping Qian, Man Li, Yueqiu Gao, Yueqiu Gao   +14 more
doaj   +1 more source

Immune dysfunction in cirrhosis. [PDF]

, 2014
Innate and adaptive immune dysfunction, also referred to as cirrhosis-associated immune dysfunction syndrome, is a major component of cirrhosis, and plays a pivotal role in the pathogenesis of both the acute and chronic worsening of liver function ...
Antal-Szalmás, Péter, Lakatos, Péter László, Papp, Mária, Sipeki, Nóra   +3 more
core   +1 more source

Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]

, 2017
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania, Andrade, Bjornsson, Chalasani, Fontana, Fontana, Fontana, Fontana, Gustot, Jalan, Karvellas, Lee, Lee, Martinez, Medina-Caliz, Olson, Ostapowicz, Robles-Diaz, Rockey, Stickel, Stravitz, Zimmerman   +21 more
core   +2 more sources