Results 231 to 240 of about 7,222,965 (284)
Acute phase protein expression in non-phatologic bovine forestomach mucosae
I. Tessaro +8 more
core +2 more sources
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Association of Bovine Respiratory Disease during the Pre-Weaning Period with Blood Cell Counts and Circulating Concentration of Metabolites, Minerals, and Acute Phase Proteins in Dairy Calves Transported to a Calf Raising Facility. [PDF]
Bielamowicz LP +6 more
europepmc +1 more source
Acute phase proteins in ruminants
The physiological response to infections and injuries involves local inflammation and the initiation of events leading to a systemic response, also called acute phase reaction (APR). This multiplicity of changes is distant from the site of injury, and includes fever, leukocytosis and quantitative and qualitative modification of a group of non ...
F. Ceciliani +3 more
openaire +3 more sources
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Acute-Phase Proteins in Alzheimer’s Disease
European Neurology, 2008The main ‘acute-phase proteins’ were determined in serum of 20 patients with presenile Alzheimer’s disease (AD) and compared with values in 18 age-matched healthy control subjects. Following parameters were evaluated: α<sub>1</sub>-antitrypsin (αAT), haptoglobin (HPT), transferrin (TRF), acidic α<sub>1</sub>-glycoprotein (A αG),
GIOMETTO B +4 more
openaire +3 more sources
1980
Many diseases demonstrate an inflammatory process which involves plasma proteins termed acute phase proteins. Fluctuations in serum levels of these proteins are now being utilised to assess diseases which involve inflammation and tissue damage. They are a useful indicator in detection, diagnosis and treatment of such diseases.
J. D. Wilson, Sandra I. Simpson
openaire +1 more source
Many diseases demonstrate an inflammatory process which involves plasma proteins termed acute phase proteins. Fluctuations in serum levels of these proteins are now being utilised to assess diseases which involve inflammation and tissue damage. They are a useful indicator in detection, diagnosis and treatment of such diseases.
J. D. Wilson, Sandra I. Simpson
openaire +1 more source

